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Psychological interventions for refugees with depression: a systematic literature review.
BMC Psychiatry
January 2025
Department of Medical Psychology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Background: Ongoing global crises are forcing an increasing number of people to seek refuge in other countries. Refugees have often experienced multiple potentially traumatic events before and during their flight and are burdened by psychosocial problems in exile. Epidemiological research suggests that many refugees suffer from depression and need psychological care.
View Article and Find Full Text PDFA Review on Medicinal Approaches of Novel Imatinib Derivatives.
Curr Top Med Chem
January 2025
Department of Pharmacy, Panipat Institute of Engineering & Technology (PIET) Samalkha, Panipat, Haryana-132102, India.
Phenyl amino pyrimidine attracts researchers due to its versatile scaffold and medicinal significance. This significant moiety present in the Imatinib contributed to medicinal chemistry. In this manuscript, we reviewed various derivatives of Imatinib containing 2-phenylaminopyrimidine, which has a variety of roles, especially in the anti-cancer category.
View Article and Find Full Text PDFSodium Glucose Cotransporter-2 Inhibitors Improve Endothelial Function and Arterial Stiffness in Diabetic Individuals: A Systematic Review and Network Meta-Analysis.
Curr Vasc Pharmacol
January 2025
Dental Post Graduate Training Department, PHCC, Manama, Kingdom of Bahrain.
Introduction: Sodium Glucose cotransporter-2 inhibitors (SGLT2is) possess pleiotropic effects, such as antioxidant, antifibrotic, anti-inflammatory, and vascular remodeling activities. Considering the lack of literature, a network meta-analysis was conducted to explore the impact of SGLT2is on endothelial dysfunction and arterial stiffness in the diabetic population.
Methods: Electronic databases were searched to identify randomized clinical trials evaluating the effects of SGLT2is on outcomes, such as Flow-mediated Vasodilation (FMV), Pulse Wave Velocity (PWV), and Augmentation Index (AIx).
Effect of exercise on kidney-relevant biomarkers in the general population: a systematic review and meta-analysis.
BMJ Open
January 2025
School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Objective: Physical activity (PA) has been generally recognised as beneficial for health. The effect of a change in PA on kidney biomarkers in healthy individuals without kidney disease remains unclear. This manuscript synthesised the evidence of the association of changes in PA with kidney biomarkers in the general population free from kidney disease.
View Article and Find Full Text PDFApplication of core functions and forms in complex health intervention research: a scoping review protocol.
BMJ Open
January 2025
Adult and Child Center for Health Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine, Aurora, Colorado, USA.
Introduction: The ability of healthcare, community and public health systems to effectively implement and disseminate research innovations depends on contextual factors at multiple interconnected levels of influence (eg, the innovation, individual, provider/implementor, organisation and health system). Recently, there has been an increase in the development of complex interventions designed to target multiple levels, designed for or adapted to the context in which they are delivered. Two concepts from complex systems thinking have been increasingly used to operationalise such interventions-core functions (theory and evidence-driven purposes of interventions) and forms (adaptable activities that perform each core function).
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