The Life-Cycle of the HIV-1 Gag-RNA Complex.

Viruses

Architecture et Réactivité de l'ARN, Université de Strasbourg, IBMC, CNRS, 15 rue René Descartes, 67084 Strasbourg, France.

Published: September 2016

Human immunodeficiency virus type 1 (HIV-1) replication is a highly regulated process requiring the recruitment of viral and cellular components to the plasma membrane for assembly into infectious particles. This review highlights the recent process of understanding the selection of the genomic RNA (gRNA) by the viral Pr55(Gag) precursor polyprotein, and the processes leading to its incorporation into viral particles.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035962PMC
http://dx.doi.org/10.3390/v8090248DOI Listing

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