Ribamidil has a cytostatic effect on bone marrow cells and a radioprotective therapeutic action. Ribamidil favors CFUs proliferation and does not interfere with the process of CFUs migration.
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Extraction, purification, structural characterization, and biological activity of polysaccharides from Aralia: A review.
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Key Laboratory of Basic and Application Research of Beiyao (Ministry of Education), Heilongjiang University of Chinese Medicine, Harbin 150040, People's Republic of China.. Electronic address:
Aralia Linn. Plants (ALPs) is a member of the Araliaceae family, a genus of more than thirty species, some plants of Aralia Linn are commonly used as herbal medicines. ALPs is commonly utilized for relieving the symptoms of neurasthenia, rheumatoid arthritis, etc.
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Flagellin stimulates Toll-like receptor 5 (TLR5), triggering both innate and adaptive immune responses, making it a potential vaccine adjuvant. On mucosal surfaces, flagellin induces a strong release of cytokines, chemokines, and immunoglobulins. When used in its free monomeric form, flagellin has been shown to enhance immune responses when combined with vaccine antigens.
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Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Ministry of Education, Shihezi University School of Medicine, Shihezi 832003, China.
The Chansu injection (CSI), a sterile aqueous solution derived from Chansu, is applied in clinical settings to support antitumor and anti-radiation treatments. CSI's principal active components, bufadienolides (≥90%), demonstrate potential effects on pancreatic cancer (PDAC), but their underlying mechanisms remain unclear. This study aimed to elucidate the antitumor effects and pathways associated with CSI in PDAC.
View Article and Find Full Text PDF[Metabolomics study on anti-radiation effect of Yiguan Decoction].
Zhongguo Zhong Yao Za Zhi
October 2024
School of Traditional Chinese Medicine,Guangdong Pharmaceutical University Guangzhou 511436, China Institute of Radiation Medicine,Academy of Military Medical Sciences,Academy of Military Sciences Beijing 100850, China.
The gas chromatography-mass spectrometer(GC-MS) metabolomics method was used to investigate the anti-radiation effect of Yiguan Decoction water extract on mice and explore its related pathways and mechanisms of action. Healthy SPF male mice from Kunming were randomly assigned to six groups: blank group, model group, positive drug group, and high-dose, medium-dose, and low-dose groups of Yiguan Decoction, with ten mice in each group. Mice were prophylactically dosed for six days, and ~(60)Co γ ray with 5 Gy was used to establish a radiation mouse model.
View Article and Find Full Text PDFExtraction, purification, structural characterization, biological activity, mechanism of action and application of polysaccharides from Ganoderma lucidum: A review.
Int J Biol Macromol
December 2024
College of Pharmacy, Shaanxi University of Chinese Medicine, Shiji Ave., Xi'an-xianyang New Economic Zone, Shaanxi Province 712046, People's Republic of China. Electronic address:
Article Synopsis
- Ganoderma lucidum, known as "fairy grass," is a traditional Chinese tonic with various beneficial chemical components that help improve overall health and treat conditions like lung issues and fatigue.
- The primary bioactive ingredient, Ganoderma lucidum polysaccharides (GLPs), has demonstrated a range of medicinal properties, including enhancing immunity and inhibiting tumor growth.
- The article reviews recent research on GLPs, covering their extraction, benefits, and potential applications in medicine, food, and consumer products, aiming to support the use of Ganoderma lucidum in traditional medicine.
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