Mounting evidence suggests that early-life conditions have an enduring effect on an individual's mortality risks as an adult. The contribution of improvements in early-life conditions to the overall decline in adult mortality, however, remains a debated issue. We provide an estimate of the contribution of improvements in early-life conditions to mortality decline after age 30 in Dutch cohorts born between 1812 and 1921. We used two proxies for early-life conditions: median height and early-childhood mortality. We estimate that improvements in early-life conditions contributed more than five years or about a third to the rise in women's life expectancy at age 30. Improvements in early-life conditions contributed almost three years or more than a quarter to the rise in men's life expectancy at age 30. Height appears to be the more important of the two proxies for early-life conditions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/00324728.2016.1223336 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Lactational exposure to perfluorooctane sulfonate remains a potential risk in brain function of middle-aged male mice.
J Physiol Sci
January 2025
Department of Integrative Physiology, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, 371-8511, Maebashi, Gunma, Japan. Electronic address:
Perfluorooctane sulfonate (PFOS) exerts adverse effects on neuronal development in young population. Limited evidences have shown that early-life PFOS exposure holds a potential risk for developing age-related neurodegenerative diseases such as Alzheimer's disease later in life. The present study investigated the effects of lactational PFOS exposure on cognitive function using one-year-old mice.
View Article and Find Full Text PDFEarly-life famine exposure and subsequent risk of chronic diseases in later adulthood: a population-based retrospective cohort study.
Front Public Health
January 2025
School of Physical Education, Shanxi Normal University, Taiyuan, China.
Background: Over the past few decades, China has experienced significant demographic and epidemiological changes. The sharp decline in fertility and mortality rates has accelerated population aging, contributing to an increase in the prevalence of chronic diseases. The nutritional condition during early life is associated with the onset of chronic illnesses later in adulthood.
View Article and Find Full Text PDFEarly age of dog exposure is negatively associated with atopic dermatitis: A comprehensive analysis.
Pediatr Res
January 2025
Department of Dermatology Hunan Engineering Research Center of Skin Health and Disease Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha, 410008, China.
Background: Currently, whether exposure to pets is a protective factor for atopic dermatitis (AD) is controversial.
Objective: To investigate the association of pet exposure in early life with the incident AD.
Methods: This study was based on PRISMA.
Sociocultural and perinatal health factors associated with Autism spectrum disorder (ASD) in children.
Compr Psychiatry
January 2025
School of Clinical Medicine, University of New South Wales, Sydney, NSW, Australia; Academic Unit of Child Psychiatry, Liverpool Hospital, Liverpool, NSW, Australia; Ingham Institute of Applied Medical Research and Liverpool Hospital, Sydney, NSW, Australia. Electronic address:
While previous research has examined perinatal factors in the context of Autism Spectrum Disorder (ASD), studies focusing on sociocultural factors is limited. We conducted a cross-sectional analysis utilizing data from the Australian Autism Biobank (AAB), which encompasses autistic children aged 2-17, their siblings, parents, and unrelated controls. Employing multivariable regression analyses, we aimed to identify factors associated with ASD across various domains, spanning health and lifestyle, perinatal, and postnatal contexts.
View Article and Find Full Text PDFApproach to the Patient: Diagnostic Challenges in the Work Up for Polycystic Ovary Syndrome.
J Clin Endocrinol Metab
January 2025
Departments of Obstetrics and Gynecology, and Medicine, University of Alabama at Birmingham, Birmingham, Alabama, 35243 USA.
Polycystic ovary syndrome (PCOS) affects 10-13% of women globally. It is a condition with metabolic, reproductive and psychological features, with health impacts across the lifespan. The aetiology of PCOS is complex, with an interplay of several factors including genetic and epigenetic susceptibility, androgen exposure in early life and adiposity related dysfunction leading to hypothalamic-ovarian disturbance.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!