Syphilis is an infectious disease with mucocutaneous lesions that are characteristic of their stage (primary, secondary, or tertiary). These are not always typical and may have other morphologies and unusual symptoms, making diagnosis difficult. The report herein is of a healthy woman with vesicular lesions associated with intense itching. The diagnosis of secondary syphilis was confirmed with VDRL 1/512 and FTA Abs positive. Histopathology showed spongiosis in the epidermis and infiltrated lymphocytes and plasma cell in the dermis. Clinical improvement occurred after the first dose of benzathine penicillin. In the literature, few cases of vesicular lesions in syphilis have been found and itching is mentioned as uncharacteristic . Histology showing spongiosis is also unusual.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Nuclear morphological characterisation of lobular carcinoma variants: a morphometric study.
Histopathology
December 2024
Academic Unit for Translational Medical Sciences, School of Medicine, University of Nottingham, Nottingham, UK.
Background And Aims: Lobular carcinoma (LC) of the breast exhibits diverse morphology and clinical behaviour. The pleomorphic variant (pLC) displays distinct cytonuclear features and aggressiveness compared to the classic variant (cLC). However, diagnosing pLC remains subjective.
View Article and Find Full Text PDFSequential Progression from Pseudo-Vesicular Lesions to Polymorphic Eruption: A Diagnostic Dilemma.
Indian J Dermatol
October 2024
Department of Dermatology, Venereology and Leprosy, King George's Medical University, Lucknow, Uttar Pradesh, India E-mail:
Giant cerebellar neurocysticercosis masquerading a primary central nervous system neoplasm - A case report with review of literature.
Surg Neurol Int
November 2024
Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Background: Neurocysticercosis (NCC) is one of the leading parasitic infections of the brain. Giant NCC is rare, with only two cases of cerebellar involvement reported till now. In the presence of a host immune response, these giant NCCs can mimic primary central nervous system neoplasms.
View Article and Find Full Text PDFClinical presentation and molecular diagnosis of a possible Mpox virus and Varicella zoster virus co-infection in an adult immunocompetent Filipino: a case report.
Front Public Health
December 2024
Research Institute for Tropical Medicine, Muntinlupa, Philippines.
We report the first travel-related case of a possible Mpox-Varicella zoster virus (VZV) co-infection in the Philippines, a country that is endemic for Varicella but non-endemic for Mpox. A 29-year-old Filipino, female, with a travel history to Switzerland and with no prior history of VZV infection sought consultation due to rashes. She presented with multiple papular, pustular, and vesicular skin lesions, some with umbilication and with irregular borders, on the face, neck, trunk, inguinal area, upper extremities, and right leg.
View Article and Find Full Text PDFEvaluating the effectiveness of topical olive leaf extract emulgel in managing recurrent herpes labialis: a randomized controlled clinical study.
Sci Rep
December 2024
Faculty of Dentistry, Oral Medicine Department, Damascus University, Damascus University, Damascus, Syria.
Recurrent herpes labialis (RHL) is a lifelong oral health issue that affects about one-third of the world's population, causing frequent, painful, and discomfort lesions. This randomized, triple-blinded study aimed to evaluate the effectiveness of olive leaf extract (OLE) compared to acyclovir cream (Veramid 5%) in managing vesicular stage of RHL lesions. Forty patients were randomly divided into two equal groups and were instructed to apply the prescribed medication five times a day for five consecutive days.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!