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| http://dx.doi.org/10.1002/14651858.ED000115 | DOI Listing |
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Comparative analysis of real-world data on the efficacy and safety of and adherence to ICS/LABA combinations in asthma management.
Respir Res
January 2025
Department of Pulmonary, Allergy, and Critical Care Medicine, Chungnam National University School of Medicine, Daejeon, South Korea.
Background: Choosing effective devices (inhaled corticosteroid [ICS]-long-acting β2 agonist [LABA] combination inhalers) as maintenance treatment is critical for managing patients with asthma. We aimed to compare ICS/LABA combination efficacy, safety, and adherence across inhaler types and components in patients newly diagnosed with asthma.
Methods: Utilizing South Korea's National Health Insurance Service data, we conducted a population-based cohort study involving patients aged 18-80 years, newly diagnosed with asthma who received ICS/LABA combination therapy between January 2016 and December 2020.
Molecular Signatures of Aeroallergen Sensitization in Respiratory Allergy: A Comparative Study Across Climate-Matched Populations.
Int J Mol Sci
December 2024
Inmunotek SL Laboratories, 28000 Madrid, Spain.
Climate change is significantly altering the dynamics of airborne allergens, affecting their seasonality, allergenicity, and geographic distribution, which correlates with increasing rates of allergic diseases. This study investigates aeroallergen sensitization among populations from Tenerife, Spain, and Lima, Peru-two regions with similar climates but distinct socio-economic conditions. Our findings reveal that Spanish individuals, particularly those with asthma, demonstrate higher sensitization levels to a broader range of allergens, especially mites, with 85% of participants reacting to at least one mite allergen.
View Article and Find Full Text PDFHistopathological, Cytological and Radiological Correlations in Allergy and Public Health Concerns: A Comprehensive Review.
J Asthma Allergy
December 2024
Department of Public Health, School of Allied Medical Sciences, Kampala International University, Western Campus, Ishaka, Bushenyi, Uganda.
Allergies represent a significant and growing public health concern, affecting millions worldwide and burdening healthcare systems substantially. Accurate diagnosis and understanding of allergy is crucial for effective management and treatment. This review aims to explore the historical evolution, current advances, and prospects of histopathological and cytological techniques in allergy diagnosis, highlighting their crucial role in modern medicine.
View Article and Find Full Text PDFFrom asthma exacerbation to pulmonary mucoepidermoid carcinoma: A rare case report.
Int J Surg Case Rep
January 2025
Department of Pathology, Al-Istishari Hospital, Ramallah, Palestine.
Introduction And Importance: Pulmonary mucoepidermoid carcinoma (PMEC) is a rare lung tumor, accounting 0.1-0.2 % of lung malignancies, commonly affecting adults under 50.
View Article and Find Full Text PDFDisease-wide association study uncovers disease continuum network of unipolar depression.
Eur Neuropsychopharmacol
December 2024
Beijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, China; Academy of Military Medical Sciences, 27 Taiping Road, Beijing 100850, China. Electronic address:
Unipolar depression is typically regarded as a psychiatric disorder, yet it frequently coexists with various major diseases. This study employs a Disease-Wide Association Study (DWAS) approach to map the disease continuum surrounding unipolar depression, analyzing data from a registry cohort of 392,423 individuals, including 43,280 diagnosed cases of unipolar depression. Significant associations were identified between depression and comorbidities across multiple organ systems, including both mental and physical disorders.
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