Objective: To determine differences in the recontamination of stethoscope membranes after cleaning with chlorhexidine, triclosan, or alcohol.
Methods: Experimental, controlled, blinded trial to determine differences in the bacterial load on stethoscope membranes. Membranes were cultured by direct imprint after disinfection with 70% isopropyl alcohol, 1% triclosan, or 1% chlorhexidine and normal use for 4 hours. As a baseline and an immediate effect control, bacterial load of membranes without disinfection and after 1 minute of disinfection with isopropyl alcohol was determined as well.
Results: Three hundred seventy cultures of in-use stethoscopes were taken, 74 from each arm. In the baseline arm the median growth was 10 CFU (interquartile range [IQR], 32-42 CFU); meanwhile, in the isopropyl alcohol immediate-effect arm it was 0 CFU (IQR, 0-0 CFU). In the arms cultured after 4 hours, a median growth of 8 CFU (IQR, 1-28 CFU) in the isopropyl alcohol arm, 4 CFU (IQR, 0-17 CFU) in the triclosan arm, and 0 CFU (IQR, 0-1 CFU) in the chlorhexidine arm were seen. No significant differences were observed between the bacterial load of the chlorhexidine arm (after 4 hours of use) and that of the isopropyl alcohol arm (after 1 minute without use) (Z= 2.41; P > .05).
Conclusions: Chlorhexidine can inhibit recontamination of stethoscope membranes and its use could help avoid cross-infection.
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http://dx.doi.org/10.1016/j.ajic.2016.07.012 | DOI Listing |
J Am Chem Soc
January 2025
Department of Chemistry, University of Texas at Austin, Austin 78712, Texas, United States.
A novel mechanism for -heteroaryl C-H functionalization via dearomative addition-hydrogen autotransfer is described. Upon exposure to the catalyst derived from RuHCl(CO)(PPh) and Xantphos, dienes - suffer hydroruthenation to form allylruthenium nucleophiles that engage in -heteroaryl addition-β-hydride elimination to furnish branched products of C-C coupling - and -. Oxidative cleavage of isoprene adducts , , , and followed by ruthenium-catalyzed dynamic kinetic asymmetric ketone reduction provides enantiomerically enriched -heteroarylethyl alcohols - and, therefrom, -heteroarylethyl amines -.
View Article and Find Full Text PDFClin Oral Investig
January 2025
School of Materials Science and Innovation, Faculty of Science, Mahidol University, Phuttamonthon 4 Road, Salaya, Phuttamonthon District, Nakhon Pathom, 73170, Thailand.
Objectives: To address the high surface roughness and poor optical properties of three-dimensional (3D) printed orthodontic clear retainers, an alternative post-processing protocol was investigated with the goal of achieving improved surface, optical, and mechanical properties while preserving dimensional accuracy.
Materials And Methods: Samples were prepared from two biocompatible methacrylate-based 3D-printing resins (Formlabs Dental LT Clear V2, NextDent OrthoFlex) and one thermoplastic material (Duran). For the 3D-printed resins, one group was post-processed by rinsing in isopropyl alcohol, while another group was centrifuged before post-curing in glycerine.
Heliyon
January 2025
Division of Oral and Maxillofacial Surgery, Faculty of Dentistry, Thammasat University, Pathum Thani, 12120, Thailand.
Objectives: To evaluate the accuracy (trueness and precision) of liquid crystal display (LCD)-printed orthognathic surgical splints under two different post-processing conditions-rinsing solvent and post-polymerization time.
Materials And Methods: An LCD 3D printer was used to create 48 surgical splints using the same reference standard tessellation language (STL) files. They were randomly assigned to two experimental studies.
Sci Rep
January 2025
Environment Division, National Institute of Oceanography and Fisheries (NIOF), Kayet Bey, Elanfoushy, Alexandria, Egypt.
In this research, the degradation of Congo red (CR) dye, as an organic pollutant in water, was investigated using microwave-induced reaction technology. This technology requires a microwave-absorbing catalyst and the 2D TiCT MXene was synthesized for that purpose. The synthesized catalyst was characterized using XRD, SEM, TEM, EDX, BET, and XPS techniques.
View Article and Find Full Text PDFAnalyst
January 2025
Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.
As a marker of human metabolism, acetone is important for lipid metabolism monitoring and early detection of diabetes. In this study, we developed a handheld biosensor for acetone based on fluorescence detection by utilizing the enzymatic reaction of secondary alcohol dehydrogenase (S-ADH) with β-nicotinamide adenine dinucleotide (NADH, = 340 nm, = 490 nm). In the reaction, NADH is oxidized when acetone is reduced to 2-propanol by S-ADH, and the acetone concentration can be measured by detecting the amount of NADH consumed in this reaction.
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