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COMPARING MESH AND COMPRESSOR NEBULIZERS IN PULMONARY FUNCTION TEST IN PEDIATRIC ASTHMA ATTACKS: A DOUBLE-BLIND RANDOMIZED COMPARATIVE CLINICAL TRIAL.
Respir Med
January 2025
Celal Bayar University, Faculty of Medicine, Department Pediatric Allergy and Immunology, Manisa, Turkey.
Objective: Asthma is a prevalent global health issue, especially affecting children in numerous countries. Our study aimed to determine the most effective nebulizer type by comparing the effects of mesh nebulizers (MNs) and compressor nebulizers (CNs) on spirometry tests in pediatric asthma attacks.
Methods: The prospective, double-blind, randomized comparative study was conducted with patients aged 7-15 presenting with asthma attacks.
The efficacy and safety of Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) on cough symptoms in adult patients with asthma, A randomized double-blind, placebo-controlled, parallel group study: Chronic Cough in Asthma (COCOA) study.
J Asthma
January 2025
Division of Respiratory Medicine and Allergology, Department of Medicine, School of Medicine, Showa University, Tokyo, Japan.
Persistent cough bothers many patients with asthma because it worsens their quality of life; therefore, it must be remedied immediately. The efficacy of triple therapy as a first-line treatment for cough remains unclear. To evaluate the effectiveness and safety of the triple therapy againts persistent cough, the clinical effect of regular treatment with fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) or placebo in adult patients with asthma was investigated.
View Article and Find Full Text PDFEnhanced breathing effort in pulmonary function tests by CO2/O2 gas mixture and barometric whole-body plethysmography in healthy and feline lower airway disease cats.
Am J Vet Res
January 2025
National Taiwan University Veterinary Hospital, National Taiwan University, Taipei, Taiwan.
Objective: Enhancing ventilatory effort during pulmonary function testing can help reveal flow limitations not evident in normal tidal breathing. This study aimed to assess the efficacy and tolerability of using a CO2/O2 gas mixture to enhance tidal breathing with a barometric whole-body plethysmography system in both healthy cats and those with feline lower airway disease (FLAD).
Methods: This prospective study included healthy cats and those with FLAD, which underwent pulmonary function testing and were exposed to a 10% CO2/90% O2 gas mixture in a barometric whole-body plethysmography chamber, with CO2 concentrations maintained within the target range of 5% to 10%.
Influence of lung function on macro- and micro-structural brain changes in mid- and late-life.
Int J Surg
January 2025
Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
Introduction: Lung function has been associated with cognitive decline and dementia, but the extent to which lung function impacts brain structural changes remains unclear. We aimed to investigate the association of lung function with structural macro- and micro-brain changes across mid- and late-life.
Methods: The study included a total of 37 164 neurologic disorder-free participants aged 40-70 years from the UK Biobank, who underwent brain MRI scans 9 years after baseline.
Residing in areas with high residential greenspace is associated with increased COPD risk and decreased lung function of adults in eastern China.
Heart Lung
January 2025
Department of Preventive Medicine, Shantou University Medical College, Shantou, Guangdong 515041, China. Electronic address:
Background: Evidence for a relation between residential greenspace and respiratory health is scarce and controversial.
Objectives: The purpose of this study was to explore the association between residential greenspace and its interaction with particulate matter (PM) and risk of chronic obstructive pulmonary disease (COPD) and lung function.
Methods: A total of 3,759 adults were recruited from Wenzhou in this study.
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