[Role of functional imaging in the definition of target volumes for lung cancer radiotherapy].

Cancer Radiother

Département de médecine nucléaire, centre de lutte contre le cancer Henri-Becquerel, rue d'Amiens, 76000 Rouen, France; Laboratoire QuantIF, EA4108-Litis, FR CNRS 3638, 1, rue d'Amiens, 76000 Rouen, France.

Published: October 2016

AI Article Synopsis

  • Functional imaging with PET can enhance lung cancer radiotherapy by enabling more precise dose delivery.
  • Only FDG PET-CT is currently validated for staging and planning in lung cancer treatment.
  • Further research is needed to refine segmentation methods, explore "dose painting" techniques, and assess the benefits of adjusting treatment plans based on PET scans taken during therapy.

Article Abstract

Functional imaging with positron emission tomography (PET) is interesting to optimize lung radiotherapy planning, and probably to deliver a heterogeneous dose or adapt the radiation dose during treatment. Only fluorodeoxyglucose (FDG) PET-computed tomography (CT) is validated for staging lung cancer and planning radiotherapy. The optimal segmentation methods remain to be defined as well as the interest of "dose painting" from pre-treatment PET (metabolism: FDG) or hypoxia (fluoromisonidazole: FMISO) and the interest of replanning based on pertherapeutic PET.

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http://dx.doi.org/10.1016/j.canrad.2016.08.121DOI Listing

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