Background: Causes and significance of interventricular conduction disorders (IVCDs) after orthotopic heart transplantation (OHT) are still unknown.
Methods: We retrospectively researched the presence of IVCDs in 240 patients who underwent bicaval OHT in three time periods: at day 1, after 1 year, and after 3 years from OHT. To evaluate the impact of the surgical technique, a control population treated with biatrial anastomosis was used.
Results: The most common IVCD was right bundle branch block (RBBB). Its presence at day 1 correlated with transpulmonary gradient before OHT. Its presence after 1 year and its development correlated with a 1-month acute rejection score≥2 (p = .050 and p = .006). The incidence of RBBB was higher in the biatrial control population (40.7% vs 23.8%, p < .001).
Conclusions: RBBB is the most common IVCD. Its presence can be explained by a susceptibility of the right branch to heart positioning, pressure overload, and acute rejection. IVCDs do not affect prognosis.
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http://dx.doi.org/10.1111/anec.12402 | DOI Listing |
BMC Cardiovasc Disord
January 2025
Department of cardiac surgery, The First Hospital of Hebei Medical University, No. 89 Donggang Road, Shijiazhuang City, 050000, Hebei Province, China.
Objective: Sarcopenia is a common complication in elderly patients with coronary heart disease (CHD). This study aims to analyse and explore the occurrence of sarcopenia in elderly patients with CHD and its associations with short-term prognosis.
Methods: A total of 318 elderly patients with CHD were enrolled between March 2020 and March 2022.
Biomaterials
January 2025
Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX, 78712, USA. Electronic address:
Direct pacing of the mid myocardium where re-entry originates can be used to prevent ventricular arrhythmias and circumvent the need for painful defibrillation or cardiac ablation. However, there are no pacing electrodes small enough to navigate the coronary veins that cross these culprit scar regions. To address this need, we have developed an injectable ionically conductive hydrogel electrode that can fill the epicardial coronary veins and transform them into flexible electrodes.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Cardiology and Electrotherapy, Faculty of Medicine, Medical University of Gdansk, 80-210 Gdansk, Poland.
A leadless pacemaker (LP) is a modern alternative to a transvenous pacemaker, allowing certain complications to be avoided; however, some cannot be eliminated. To highlight the essential role of advanced speckle-tracking echocardiography (STE) in diagnosing pacing-induced cardiomyopathy (PICM) caused by an LP. A 79-year-old male, after LP implantation a year earlier, was admitted due to heart failure (HF).
View Article and Find Full Text PDFBiomedicines
December 2024
Department of Internal Medicine, Pusan National University School of Medicine and Cardiology, Cardiovascular Center and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 50612, Republic of Korea.
Background: Current treatments for hypertrophic obstructive cardiomyopathy (HOCM), including medication, surgery, and alcohol septal ablation (ASA), have limitations in terms of efficacy and safety. To address these challenges, we developed the trans-coronary intra-septal radiofrequency ablation (TIRA) device.
Methods: This first-in-human trial was conducted to assess the efficacy and safety of the TIRA device.
Egypt Heart J
January 2025
Department of Cardiology, Hangzhou First People's Hospital, #261 Huansha Road, Hangzhou, 310000, Zhejiang Province, China.
Background: To investigate the optimization of leadless pacemaker placement and to assess its impact on heart synchronization and tricuspid regurgitation.
Results: A clinical trial was conducted involving 53 patients who underwent leadless pacemaker implantation at the Second Affiliated Hospital of Zhejiang University School of Medicine and Hangzhou First People's Hospital between March 2022 and February 2023. Implantation site localization was determined using the 18-segment method under RAO 30° imaging.
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