AI Article Synopsis

  • A 74-year-old Japanese woman with no prior health issues was hospitalized due to fever and high levels of C-reactive protein.
  • She showed symptoms resembling Behçet’s disease, including mouth ulcers, intestinal problems, and a specific skin rash.
  • During her treatment, she developed a significant increase in monocytic cells in her blood, leading to a diagnosis of acute monocytic leukemia, with the leukemic cells identified in both her skin and intestines.

Article Abstract

A previously healthy 74-year-old Japanese female was hospitalized with fever and high C-reactive protein. She developed palatal herpangina-like aphthous ulcers, localized intestinal wall thickening, terminal ileum ulcers, and an erythematous acneiform rash; thus Behçet's disease-like illness was suspected. Significant peripheral blood acute monocytosis developed during her hospitalization and acute monocytic leukemia (FAB M5b) with normal karyotype was diagnosed. By immunostaining, the infiltrating cells in the skin and the terminal ileum were identified as monocytic leukemic cells. This case exhibited a unique initial presentation of Behçet's disease-like illness associated with acute monocytic leukemia.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004031PMC
http://dx.doi.org/10.1155/2016/4231276DOI Listing

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