Investigation of titania nanoparticles on behaviour and mechanosensory organ of Drosophila melanogaster.

Titania nanoparticles are used in food, cosmetic, medicine, paint and many more domestic items. Its extensive use has raised the threat to the physiological system and thus the functioning of the body. In the current study, the toxicity of TiO is checked by adding it in food and using Drosophila melanogaster as a model organism. Various concentrations of TiO (50, 100, 200, 250mg·L) toxicity was assessed via oral route exposure. Survivability, life-cycle, mechanosensory behaviour and structure of various mechanosensory organs were monitored as a read out of nanoparticle toxicity. TiO NPs generate reactive oxygen species which can modify multiple signalling pathways and thus can alter the development and behavioural pattern of the fly.