In the past three decades, we have learned much about the potential short-term and long-term safety issues associated with the intravenous administration of gadolinium based contrast agents (GBCAs). Yet, surprisingly, the past few years and even months have been accompanied by new discoveries in this field. This manuscript focuses predominantly on what we have learned - and are continuing to learn - about the long-term potential MR safety issues associated with the administration of the various GBCAs available today and will highlight areas in which they appear to differ from each other at least in a quantitative fashion, if not qualitatively.
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http://dx.doi.org/10.1016/j.mri.2016.08.017 | DOI Listing |
Commun Chem
January 2025
Faculty of Engineering, Hokkaido University, Kita 13, Nishi 8, Kita-ku, Sapporo, Hokkaido, 060-8628, Japan.
Photoinduced metal-to-ligand (or ligand-to-metal) charge-transfer (CT) states in metal complexes have been extensively studied toward the development of luminescent materials. However, previous studies have mainly focused on CT transitions between d- and π-orbitals. Herein, we report the demonstration of CT emission from 4f- to π-orbitals using a trivalent europium (Eu(III)) complex, supported by both experimental and theoretical analyses.
View Article and Find Full Text PDFInt J Cardiovasc Imaging
January 2025
Cardiovascular MR R&D, Siemens Medical Solutions USA, Inc., Chicago, IL, USA.
Parametric mapping has become a standard of care technique for the non-invasive assessment of myocardial edema and fibrosis. Conventional MOLLI-based T1 mapping is susceptible to many confounding effects particularly in the pediatric population. The requirement for compliant breath holds is a major limitation for younger or more ill patients.
View Article and Find Full Text PDFJ Cardiovasc Magn Reson
January 2025
West Herts Teaching Hospitals NHS Trust, Watford, UK; Institute of Clinical Sciences, Imperial College, London, UK.
Objectives: To examine the provision of cardiovascular magnetic resonance (CMR) using gadolinium-based contrast agents (GBCA) in patients with chronic kidney disease (CKD).
Methods: An electronic survey was sent to the service leads of all CMR units in the UK in October 2022 requesting information on current departmental protocols and practice.
Results: A response rate of 55% was achieved from the 82 UK CMR units surveyed.
J Formos Med Assoc
January 2025
Department of Radiology, National Taiwan University Hospital, Taipei, Taiwan.
Contrast media are essential agents that enhance the diagnostic capabilities of imaging studies, such as computed tomography and magnetic resonance imaging. However, concerns regarding the risk of adverse events have led to cautious use in patients with chronic kidney disease. A multidisciplinary review by nephrologists, cardiologists, and radiologists at National Taiwan University Hospital examined evidence linking iodinated contrast media and gadolinium-based contrast agents with acute kidney injury and nephrogenic systemic fibrosis.
View Article and Find Full Text PDFRev Cardiovasc Med
January 2025
Department of Radiology, Affiliated Hospital of North Sichuan Medical College, 637000 Nanchong, Sichuan, China.
Dilated cardiomyopathy (DCM) is the ultimate manifestation of the myocardial response to various genetic and environmental changes and is characterized mainly by impaired left ventricular systolic and diastolic function. DCM can ultimately lead to heart failure, ventricular arrhythmia (VA), and sudden cardiac death (SCD), making it a primary indication for heart transplantation. With advancements in modern medicine, several novel techniques for evaluating myocardial involvement and disease severity from diverse perspectives have been developed.
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