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Early outcomes after small incision lenticule extraction and photorefractive keratectomy for correction of high myopia. | LitMetric

AI Article Synopsis

  • A study compared visual and refractive outcomes in patients with high myopia and myopic astigmatism who underwent either small-incision lenticule extraction (SMILE) or photorefractive keratectomy (PRK) with mitomycin C.
  • At 1 month post-surgery, SMILE patients showed better uncorrected distance visual acuity and efficacy index compared to PRK, although by 6 months, both procedures yielded comparable corrected distance visual acuity and safety indices.
  • However, significant differences in postoperative spherical equivalent and cylinder measurements favored SMILE, with 100% of SMILE patients achieving close to the desired cylindrical correction versus 69% in the PRK group, highlighting a trend of over

Article Abstract

We prospectively compared visual and refractive outcomes in patients with high myopia and myopic astigmatism after small-incision lenticule extraction (SMILE) and photorefractive keratetctomy (PRK) with mitomycin C. Sixty-six eyes of 33 patients (mean age, 29.7 ± 5.6 years) were included (SMILE: 34 eyes, PRK 32 eyes). Preoperatively, no significant difference was noted in manifest spherical equivalent (p = 0.326), manifest sphere (p = 0.277), and manifest cylinder (p = 0.625) between both groups. At 1 month, there were significant differences in logMAR uncorrected distance visual acuity, efficacy index and manifest refraction spherical equivalent between SMILE and PRK (p ≤ 0.029). At 6 months, the logMAR corrected distance visual acuity (p = 0.594), logMAR uncorrected visual acuity (p = 0.452), efficacy index (p = 0.215) and safety index was (p = 0.537) was comparable between SMILE and PRK. Significant differences were observed in postoperative manifest spherical equivalent (p = 0.044) and manifest cylinder (p = 0.014) between both groups. At the end of 6 months, 100% of the eyes in SMILE group and 69% of the eyes in PRK group were within ±0.50 D of the attempted cylindrical correction. The postoperative difference vector, magnitude of error and absolute angle of error were significantly smaller after SMILE compared to PRK (p ≤ 0.040) implying a trend towards overcorrection of cylindrical correction following PRK.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013393PMC
http://dx.doi.org/10.1038/srep32820DOI Listing

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