A Kinetic Self-Sorting Approach to Heterocircuit [3]Rotaxanes.

Angew Chem Int Ed Engl

School of Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, UK.

Published: September 2016

AI Article Synopsis

  • The study introduces a new method called active-template coupling to enhance the production of a specific molecular structure known as a [3]rotaxane.
  • This method allows the system to self-sort, meaning it can selectively increase the quantity of the desired product while reducing other unwanted threaded components.
  • The approach is presented as a proof-of-concept, demonstrating the potential for optimizing molecular design through kinetic processes.

Article Abstract

In this proof-of-concept study, an active-template coupling is used to demonstrate a novel kinetic self-sorting process. This process iteratively increases the yield of the target heterocircuit [3]rotaxane product at the expense of other threaded species.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113769PMC
http://dx.doi.org/10.1002/anie.201606640DOI Listing

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