Modern analytical techniques can determine a multitude of fungal metabolites contaminating food and feed. In addition to known mycotoxins, for which maximum levels in food are enforced, also currently unregulated, so-called "emerging mycotoxins" were shown to occur frequently in agricultural products. The aim of this review is to critically discuss the relevance of selected emerging mycotoxins to food and feed safety. Acute and chronic toxicity as well as occurrence data are presented for enniatins, beauvericin, moniliformin, fusaproliferin, fusaric acid, culmorin, butenolide, sterigmatocystin, emodin, mycophenolic acid, alternariol, alternariol monomethyl ether, and tenuazonic acid. By far not all of the detected compounds are toxicologically relevant at their naturally occurring levels and are therefore of little or no health concern to consumers. Still, gaps in knowledge have been identified for several compounds. These gaps should be closed by the scientific community in the coming years to allow a proper risk assessment.
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http://dx.doi.org/10.1021/acs.jafc.6b03413 | DOI Listing |
Food Chem
December 2024
School of Chemistry and Chemical Engineering, Shanxi Provincial Key Laboratory of Chemical Biosensing, Shanxi Datong University, Datong 037009, PR China. Electronic address:
Food safety is a pressing global public issue that has garnered significant attention worldwide, especially recent outbreaks of foodborne illnesses. The use of emerging porous materials enables the development of effective and durable detection methods for the detection of food contaminants. Covalent organic frameworks (COFs), as a class of emerging porous crystalline materials, rendered with the advantage of large specific surface area, highly controllable and ordered structures, diverse pore structures, high stability, and controllable surface functionalization.
View Article and Find Full Text PDFMucormycosis is an emerging, life-threatening human infection caused by fungi of the order Mucorales. Metabolic disorders uniquely predispose an ever-expanding group of patients to mucormycosis via poorly understood mechanisms. Therefore, it is highly likely that uncharacterized host metabolic effectors confer protective immunity against mucormycosis.
View Article and Find Full Text PDFInt J Microbiol
December 2024
Department of Biology, Laboratory of Research and Development in Engineering Sciences, Faculty of Sciences and Techniques of Al-Hoceima, Abdelmalek Essaadi University, Tetouan 93000, Al-Hoceima, Morocco.
Research into biologically natural substances with antitumor properties, known for their potential to induce fewer side effects and exhibit specificity toward cancerous cells, remains imperative. The pressing demand for novel agents in cancer therapy underscores the intensive investigation of natural products from microorganisms. , frequently isolated from food and feed, emerges as a promising candidate against pathogenic bacteria and fungi.
View Article and Find Full Text PDFFungal Biol
December 2024
Department of Sustainable Crop Production, Università Cattolica del Sacro Cuore, 29122, Piacenza, Italy. Electronic address:
Apples and apple-derived products can be contaminated with patulin and, to a lesser extent, aflatoxin B1 and fumonisins. Fruits were collected from Golden Delicious and Imperatore trees in three orchards in Veneto, Northern Italy, and analysed for the presence of fungi and mycotoxins. Sampling and analyses were also carried out from storage bins to final puree tanks along the apple-puree production chain.
View Article and Find Full Text PDFAnal Chem
December 2024
Department of Analytical Chemistry, Faculty of Chemistry, Complutense University of Madrid, Ciudad Universitaria, 28040 Madrid, Spain.
The neurotoxin α-cyclopiazonic acid (CPA) is an emerging mycotoxin produced as a secondary metabolite by several fungi species (., spp. and spp.
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