It was shown for the first time that the endogenous cyclic dipeptide cycloprolylglycine (CPG) at concentrations of 10(-7) and 10(-3) M and piracetam at a concentration of 10(-3) M increased the content of brainderived neurotrophic factor (BDNF) in the culture of neuronal cells in normal state and under conditions of glutamate and 6-oxydopamine neurotoxicity. This may indicate the possible involvement of BDNF in the mechanism of action of neuropeptide CPG and piracetam.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1134/S1607672916040104 | DOI Listing |
Publication Analysis
Top Keywords
neurotrophic factor
8
neuronal cells
8
neuropeptide cycloprolylglycine
4
cycloprolylglycine increases
4
increases levels
4
levels brain-derived
4
brain-derived neurotrophic
4
factor neuronal
4
cells time
4
time endogenous
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!