AI Article Synopsis
- The study aimed to evaluate the occurrence and implications of persistent right umbilical vein (PRUV) in a cohort from South India, finding it in 23 cases out of 20,452 births, resulting in an incidence rate of 0.11%.
- The median age of mothers was 24 years, with the diagnosis typically made around 23 weeks of gestation; intrahepatic drainage was observed in most cases, while some had absent ductus venosus.
- Over half of the cases (52.2%) had additional significant abnormalities, mainly cardiovascular issues, but a good postnatal outcome was noted in 60.9% when associated anomalies were minor or absent.
Article Abstract
The objective of our study was to appraise the incidence and significance of persistent right umbilical vein (PRUV), the most common foetal venous aberration. Based on a south Indian antenatal cohort, we identified 23 cases of PRUV amongst 20,452 foetuses of consecutive pregnancies, from 2009 to 2014, yielding an incidence of 1 in 889 total births (0.11%). The median maternal age was 24 (IQR, 22-26) years, and median gestational age at diagnosis was 23 (IQR, 22-24) weeks. Intrahepatic drainage of PRUV was seen in 91.3% cases. In three cases (13%), ductus venosus was absent. In 52.2% of the cases, additional major abnormalities were observed - predominantly cardiovascular (39.1%). The common minor marker was single umbilical artery (13%). The karyotype was found to be normal in six cases (26%) which underwent invasive testing. When associated anomalies were inconsequential or absent, the postnatal outcome was good, which reflected in 60.9% of our cases.
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| http://dx.doi.org/10.1080/01443615.2016.1196171 | DOI Listing |
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