AI Article Synopsis
- Recent advancements in treatment for oligometastatic cancer have created a need for better biomarkers to identify patients who would benefit from these therapies.
- Multimodal imaging techniques can enhance the assessment of metastatic sites and treatment response, playing a significant role in patient prognosis and treatment planning.
- By integrating traditional imaging with new methods, we can uncover detailed tumor biology and improve personalized treatment strategies for patients with extracranial oligometastases.
Article Abstract
With the advent of novel treatment strategies to help widen the therapeutic window for patients with oligometastatic cancer, improved biomarkers are needed to reliably define patients who can benefit from these treatments. Multimodal imaging is one such option and should be optimised to comprehensively assess metastatic sites, disease burden, and response to neoadjuvant treatment in each disease setting. These features will probably remain important prognostic biomarkers, and are crucial in planning multidisciplinary treatment. There are opportunities to extract additional phenotypic information from conventional imaging, while novel imaging techniques can also reveal specific aspects of tumour biology. Imaging can both characterise and localise the phenotypic heterogeneity of multiple tumour sites. Novel approaches to existing imaging datasets and correlation with tumour biology will be important in realising the potential of imaging to guide treatment in the oligometastatic setting. In this Personal View, we discuss the current status and future directions of imaging before treatment in patients with extracranial oligometastases.
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| http://dx.doi.org/10.1016/S1470-2045(16)30277-7 | DOI Listing |
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