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File: /var/www/html/application/controllers/Detail.php
File: /var/www/html/index.php
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File: /var/www/html/application/controllers/Detail.php
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Human platelets antigens influence the viral load of platelets after the interaction of the platelets with HCV and HIV in vitro. | LitMetric
Introduction : In this study, we evaluated hepatitis C virus (HCV) and human immunodeficiency virus (HIV) - platelet interactions in vitro as well as human platelets antigen (HPA) polymorphisms.Methods : Platelets were obtained from 100 healthy HPA-genotyped volunteer donors and incubated with HIV or HCV. The viral load after in vitro exposure was detected.Results : The viral load in the platelets after exposure to the virus was higher in the HIV exposure than in the HCV exposure.Conclusions : HIV-platelet ligation could be more efficient than HCV-platelet interaction. Further, the HPA-1b allele seems to influence the interaction of platelets with HCV.
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