The structural and mechanical properties of thin films generated from two types of mucins, namely, bovine submaxillary mucin (BSM) and porcine gastric mucin (PGM) in aqueous environment were investigated with several bulk and surface analytical techniques. Both mucins generated hydrated films on hydrophobic polydimethylsiloxane (PDMS) surfaces from spontaneous adsorption arising from their amphiphilic characteristic. However, BSM formed more elastic films than PGM at neutral pH condition. This structural difference was manifested from the initial film formation processes to the responses to shear stresses applied to the films. Acidification of environmental pH led to strengthening the elastic character of BSM films with increased adsorbed mass, whereas an opposite trend was observed for PGM films. We propose that this contrast originates from that negatively charged motifs are present for both the central and terminal regions of BSM molecule, whereas a similar magnitude of negative charges is localized at the termini of PGM molecule. Given that hydrophobic motifs acting as an anchor are also localized in the terminal region, electrostatic repulsion between anchoring units of PGM molecules on a nonpolar PDMS surface leads to weakening of the mechanical integrity of the films.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.langmuir.6b02057 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Direct Observation of All-Flat Bands Phononic Metamaterials.
Phys Rev Lett
December 2024
University of Connecticut, University of Connecticut, School of Mechanical, Aerospace, and Manufacturing Engineering, Storrs, Connecticut 06269, USA and Institute of Materials Science, Storrs, Connecticut 06269, USA.
Flat lines within a band structure represent constant frequency bands for all momentum values (i.e., they maintain zero group velocity for all wave numbers).
View Article and Find Full Text PDFMultimodal Study of Murine Cardiovascular Remodeling: Four-Dimensional Ultrasound and Mass Spectrometry Imaging.
J Vis Exp
January 2025
Mechanical, Aerospace, and Biomedical Engineering, University of Tennessee;
Cardiovascular disease (CVD) is the leading cause of death in the United States. Damage in the cardiovascular system can be due to environmental exposure, trauma, drug toxicity, or numerous other factors. As a result, cardiac tissue and vasculature undergo structural changes and display diminished function.
View Article and Find Full Text PDFBioinspired Antiswelling Hydrogel Sensors with High Strength and Rapid Self-Recovery for Underwater Information Transmission.
ACS Appl Mater Interfaces
January 2025
School of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix Composites, Frontiers Science Center for Transformative Molecules, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China.
Hydrogel-based sensors typically demonstrate conspicuous swelling behavior in aqueous environments, which can severely compromise the mechanical integrity and distort sensing signals, thereby considerably constraining their widespread applicability. Drawing inspiration from the multilevel heterogeneous structures in biological tissues, an antiswelling hydrogel sensor endowed with high strength, rapid self-recovery, and low swelling ratio was fabricated through a water-induced phase separation and coordination cross-linking strategy. A dense heterogeneous architecture was developed by the integration of "rigid" quadridentate carboxyl-Zr coordination bonds and "soft" hydrophobic unit-rich regions featuring π-π stacking and cation-π interactions into the hydrogels.
View Article and Find Full Text PDFMulti-step functionalization of hydrogels through mechano- and photo-responsive linkages.
Mater Horiz
January 2025
School of Chemistry, UNSW Sydney, Sydney, NSW 2052, Australia.
Patterning soft materials with cell adhesion motifs can be used to emulate the structures found in natural tissues. While patterning in tissue is driven by cellular assembly, patterning soft materials in the laboratory most often involves light-mediated chemical reactions to spatially control the presentation of cell binding sites. Here we present hydrogels that are formed with two responsive crosslinkers-an anthracene-maleimide adduct and a disulfide linkage-thereby allowing simultaneous or sequential patterning using force and UV light.
View Article and Find Full Text PDFSimilitude laws for the vibroacoustic response of fluid-loaded plates under a turbulent boundary layer excitation.
J Acoust Soc Am
January 2025
Naval Group Research, 199 av. Pierre-Gilles de Gennes, Ollioulles, 83190 France.
The theory of similitudes provides simple laws by which the response of one system (usually of small size) can be used to predict the response of another system (usually larger). This paper establishes the exact conditions and laws of similitude for the vibrations and acoustic radiation of a panel immersed in a heavy fluid and excited by a turbulent boundary layer. Previous work on vibroacoustic similitude had not considered the problem of a panel radiating in heavy fluid, for which the radiation impedance of the structure must be scaled.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!