A general process for the synthesis of alkynyl mono and dimetallic metallocenes and half-sandwich complexes has been developed. This approach uses the addition of lithium derivatives of sandwich or half-sandwich complexes to arylsulfonylacetylenes. The reaction occurs in two steps (lithiation and anti-Michael addition to alkynylsulfone followed by elimination of the ArSO moiety) to form the corresponding mono- or bimetallic alkynes in clearly higher yields, simpler experimental procedures, and more environmentally benign conditions than those of the so far reported for the synthesis of this type of products. The electrochemical properties of the newly obtained complexes have also been studied.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/chem.201603462 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Anilido-Oxazoline-Ligated Iron Alkoxide Complexes for Living Ring-Opening Polymerization of Cyclic Esters with Controllability.
Inorg Chem
December 2024
Department of Chemistry, The Hong Kong University of Science and Technology, Kowloon, Hong Kong 999077, China.
Anilido-oxazoline-ligated iron complexes, including bis(anilido-oxazolinate) iron(II), mononuclear iron(II) alkyl and aryloxide, as well as the dinuclear analogues, were synthesized, and their catalytic performance on ring-opening polymerization (ROP) has been studied. Transmetalation of FeCl(THF) with in situ-generated anilido-oxazolinate lithium afforded the bis(anilido-oxazolinate) iron complexes and . Half-sandwich anilido-oxazolinate iron trimethylsilylalkyl complexes and could be synthesized in good yields via taking pyridine as an L-type ligand.
View Article and Find Full Text PDFAn artesunate-modified half-sandwich iridium(iii) complex inhibits colon cancer cell proliferation and metastasis through the STAT3 pathway.
RSC Chem Biol
December 2024
Jiangsu Collaborative Innovation Center of Biomedical Functional Materials/Nanjing Drum Tower Hospital, College of Chemistry and Materials Science, Nanjing Normal University Nanjing 210023 China
Colon cancer is one of the most commonly diagnosed cancers and is recognized as the most aggressive tumor of the digestive system. Aberrant activation of signal transducer and activator of transcription 3 (STAT3) is associated with proliferation, metastasis and immunosuppression of the tumor cells. Here, to inhibit the STAT3 pathway and suppress metastasis in colon cancer cells, the half-sandwich iridium complex Ir-ART containing an artesunate-derived ligand was synthesized.
View Article and Find Full Text PDFTheoretical Prediction of Divalent Actinide Borozene Complexes.
Molecules
December 2024
Laboratory of Nuclear Energy Chemistry, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China.
The aromatic boron cluster B () has similar π bonding to CH, which is named "borozene". The B ligand has been observed to stabilize monovalent Ln(+I) in -LnB (Ln = La, Pr, Tb, Tm, and Yb) borozene complexes. Low-valency actinide complexes have been reported more rarely, and B may be one of the potential ligands.
View Article and Find Full Text PDFTriphenylphosphine-Modified Iridium, Rhodium, and Ruthenium Complexes to Achieve Enhanced Anticancer Selectivity by Targeting Mitochondria.
Inorg Chem
December 2024
Key Laboratory of Life-Organic Analysis of Shandong Province, Key Laboratory of Green Natural Products and Pharmaceutical Intermediates in Colleges and Universities of Shandong Province, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, P. R. China.
The incorporation of an organelle-targeting moiety into compounds has proven to be an effective strategy in the development of targeted anticancer drugs. We herein report the synthesis, characterization, and biological evaluation of novel triphenylphosphine-modified half-sandwich iridium, rhodium, and ruthenium complexes. The primary goal was to enhance anticancer selectivity through mitochondrial targeting.
View Article and Find Full Text PDFDysprosium single-molecule magnets (SMMs) with two mutually -anionic ligands have shown large crystal field (CF) splitting, giving record effective energy barriers to magnetic reversal ( ) and hysteresis temperatures ( ). However, these complexes tend to be bent, imposing a transverse field that reduces the purity of the projections of the CF states and promotes magnetic relaxation. A complex with only one charge-dense anionic ligand could have more pure CF states, and thus high and .
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!