In this paper, multi-layer feed forward neural networks are used to predict the lower heating value of gas (LHV), lower heating value of gasification products including tars and entrained char (LHV) and syngas yield during gasification of municipal solid waste (MSW) during gasification in a fluidized bed reactor. These artificial neural networks (ANNs) with different architectures are trained using the Levenberg-Marquardt (LM) back-propagation algorithm and a cross validation is also performed to ensure that the results generalise to other unseen datasets. A rigorous study is carried out on optimally choosing the number of hidden layers, number of neurons in the hidden layer and activation function in a network using multiple Monte Carlo runs. Nine input and three output parameters are used to train and test various neural network architectures in both multiple output and single output prediction paradigms using the available experimental datasets. The model selection procedure is carried out to ascertain the best network architecture in terms of predictive accuracy. The simulation results show that the ANN based methodology is a viable alternative which can be used to predict the performance of a fluidized bed gasifier.
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http://dx.doi.org/10.1016/j.wasman.2016.08.023 | DOI Listing |
Eur J Pharm Sci
January 2025
Faculty of Pharmacy, University of Ljubljana, 1000 Ljubljana, Slovenia; KRKA, d. d., 8501 Novo Mesto, Slovenia.
One of the main concerns with formulations containing amorphous solid dispersions (ASDs) is their physical stability. Stability can be compromised if a formulation contains any residual crystallinity of an active pharmaceutical ingredient (API) that could act as seeds for further crystallisation. This study presents four methods for crystalline amlodipine maleate quantification in ASD, which were developed using one Raman and three NIR process analysers.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
School of Civil and Transportation Engineering, Guangdong University of Technology, Guangzhou 510006, PR China. Electronic address:
Groundwater is widely threatened by hazardous manganese and ammonia. In present study, a novel gravity-driven fixed-bed ceramic membrane filtration (GDFBCM) with critical PAC-MnOx-ceramsite filters was built to address these issues. Static ceramsite filters in GDCM significantly increased membrane flux from 11 L/m·h to 18 L/m·h on the 50th day of filtration.
View Article and Find Full Text PDFWaste Manag
January 2025
Energy and Sustainability Department (EES), Federal University of Santa Catarina (UFSC), 88905-120, Araranguá, SC, Brazil. Electronic address:
Proper waste management and sustainable energy production are crucial for human development. For this purpose, this study evaluates the impact of blending percentage on energy recovery potential and environmental benefits of co-combustion of wastewater sludge and Brazilian low-rank coal. The sludge and coal were characterised in terms of their potential as fuel and co-combustion tests were carried out in a pilot-scale bubbling fluidised bed focused on the influence of the percentage of sludge mixture on the behaviour of co-combustion with coal in terms of flue gas composition and fluidised bed temperature stability.
View Article and Find Full Text PDFPharmaceutics
December 2024
Faculty of Pharmacy, University of Ljubljana, 1000 Ljubljana, Slovenia.
Active pharmaceutical ingredient (API) content is a critical quality attribute (CQA) of amorphous solid dispersions (ASDs) prepared by spraying a solution of APIs and polymers onto the excipients in fluid bed granulator. This study presents four methods for quantifying API content during ASD preparation. Raman and three near-infrared (NIR) process analysers were utilized to develop methods for API quantification.
View Article and Find Full Text PDFFood Eng Rev
August 2024
Department of Biosystems Engineering, University of Manitoba, E2-376, EITC, 75A Chancellor's Circle, Winnipeg, MB, R3T 2N2 Canada.
Drying is a crucial unit operation within the functional foods and biopharmaceutical industries, acting as a fundamental preservation technique and a mechanism to maintain these products' bioactive components and nutritional values. The heat-sensitive bioactive components, which carry critical quality attributes, necessitate a meticulous selection of drying methods and conditions backed by robust research. In this review, we investigate challenges associated with drying these heat-sensitive materials and examine the impact of various drying methods.
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