Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990594 | PMC |
| http://dx.doi.org/10.18240/ijo.2016.08.25 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Association of Epstein-Barr virus (EBV) with nasopharyngeal carcinoma: Experience from a North Indian tertiary care hospital.
Indian J Med Microbiol
September 2024
Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India; Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India. Electronic address:
Introduction: Nasopharyngeal carcinoma (NPC), arising from nasopharyngeal epithelium is caused by Epstein-Barr virus (EBV). It is common in South China, South East Asia and North East India. The aim and objectives of this study were to determine the prevalence of EBV in formalin-fixed paraffin-embedded (FFPE) tissue sections of clinically suspected NPC patients, correlate the results of polymerase chain reaction (PCR) with histopathology findings, and to determine the utility of tissue EBV DNA as a diagnostic bio-marker.
View Article and Find Full Text PDFHyperfractionation compared with standard fractionation in intensity-modulated radiotherapy for patients with locally advanced recurrent nasopharyngeal carcinoma: a multicentre, randomised, open-label, phase 3 trial.
Lancet
March 2023
Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, China; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China; Cooperative Surgical Ward of Nasopharyngeal Carcinoma, Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China; Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou, China. Electronic address:
Article Synopsis
- This study aimed to compare the effectiveness and safety of hyperfractionated radiotherapy versus standard fractionation for patients with advanced recurrent nasopharyngeal carcinoma who previously received high-dose radiation.
- From July 2015 to December 2019, 144 eligible patients were enrolled in a phase 3 trial, with equal random assignment to either treatment group (72 each).
- The primary goals were to assess severe late complications and overall survival, with findings indicating that hyperfractionation might reduce late toxicity compared to standard approaches.
Epstein-Barr virus dynamics and its prognostic impact on nasopharyngeal cancers in a non-endemic region.
Ecancermedicalscience
December 2022
Department of Radiation Oncology, Regional Cancer Centre, Trivandrum, Kerala 695011, India (Current address: Director - Radiation and Allied Services, KARKINOS, Ernakulum, Kerala 682017, India).
Background: Epstein-Barr virus (EBV) DNA quantification in nasopharyngeal cancer (NPC) is an indicator of the tumour burden, stage and survival. Although EBV dynamics in endemic regions has been extensively studied and reported, the data from non-endemic regions is sparse. This study attempts to investigate the EBV dynamics in NPC patients from a non-endemic region and also to identify the factors impacting the outcomes.
View Article and Find Full Text PDFEndoscopic surgery compared with intensity-modulated radiotherapy in resectable locally recurrent nasopharyngeal carcinoma: a multicentre, open-label, randomised, controlled, phase 3 trial.
Lancet Oncol
March 2021
Department of Otolaryngology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou Key Laboratory of Otorhinolaryngology, Otorhinolaryngology Institute of Sun Yat-sen University, Guangzhou, China; Department of Otolaryngology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. Electronic address:
Background: The role of surgery compared with reirradiation in the primary treatment of patients with resectable, locally recurrent nasopharyngeal carcinoma (NPC) who have previously received radiotherapy is a matter of debate. In this trial, we compared the efficacy and safety outcomes of salvage endoscopic surgery versus intensity-modulated radiotherapy (IMRT) in patients with resectable locally recurrent NPC.
Methods: This multicentre, open-label, randomised, controlled, phase 3 trial was done in three hospitals in southern China.
Primary lymphoepthelial carcinoma of the parotid gland, pictorial review of a rare entity.
J Med Imaging Radiat Oncol
June 2018
Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Lymphoepithelial carcinoma (LEC) is a rare malignancy of the salivary gland arising from the parotid in 80% of cases. LEC is indistinguishable histologically from more common non-keratinising undifferentiated nasopharyngeal carcinoma (NPC). Up to 40% of patients with primary LEC present with a cervical metastasis and histological assessment of the primary lesion or nodal metastasis may be reported as NPC.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!