Purpose Of Review: Anisocoria is a finding seen on a daily basis in nearly every eye clinic. Although often benign, it can also represent the sole sign of a life-threatening disease making an up-to-date understanding of pathophysiology and diagnosis essential for anyone practicing medicine.
Recent Findings: Many aspects of the traditional approach to anisocoria still hold true today, but advancements in imaging technology and changing trends in pharmacologic diagnosis and localization have led many to rethink that approach. In addition, the differential diagnosis for anisocoria continuously expands with identification and improved understanding of causal disease processes.
Summary: The present article discusses an approach to the classic anisocoria diagnostic algorithm modified by current knowledge from the most recent literature.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/ICU.0000000000000316 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Magnetic Resonance Imaging-Guided Frameless Stereotactic Injections of the Bilateral Cerebellar Dentate Nuclei in Nonhuman Primates: Technical Note.
Oper Neurosurg (Hagerstown)
February 2024
Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Background And Objectives: Nonhuman primates (NHPs) are important preclinical models for evaluating therapeutics because of their anatomophysiological similarities to humans, and can be especially useful for testing new delivery targets. With the growing promise of cell and gene therapies for the treatment of neurological diseases, it is important to ensure the accurate and safe delivery of these agents to target structures in the brain. However, a standard guideline or method has not been developed for stereotactic targeting in NHPs.
View Article and Find Full Text PDFApproach to anisocoria in the emergency department.
Am J Emerg Med
July 2023
Department of Emergency Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC, United States. Electronic address:
Anisocoria describes asymmetric pupillary diameter, which can result from traumatic, pharmacologic, inflammatory, or ischemic effects on the eye. In many cases, anisocoria represents a normal physiologic variant. Morbidity associated with anisocoria is directly related to the inciting cause and can vary from benign to life-threatening.
View Article and Find Full Text PDFClinical Reasoning: Acute Monocular Vision Loss in a Patient With Ipsilateral Extracranial Chronic Internal Carotid Artery Occlusion.
Neurology
July 2023
From the Humanitas University (A.A., N.B., E.C.); IRCCS Humanitas Research Hospital (S.M.L., D.A., S.M., U.P.), Milan; Università dell'Insubria (N.B.), Varese, Italy.
We report the case of a middle-aged man who presented with acute painless monocular vision loss. His medical history was remarkable for chronic total occlusion of the ipsilateral internal carotid artery (ICA) and a recent carotid endarterectomy (CEA) on the contralateral ICA. In a stepwise multidisciplinary approach assessment, we review the differential diagnosis of acute vision loss and investigate how the patient's intracranial and extracranial hemodynamic reorganization after chronic ICA occlusion may affect the clinical reasoning.
View Article and Find Full Text PDFAsymmetric Bilateral Traumatic Epidural Hematoma: A Report of a Rare Traumatic Lesion.
Korean J Neurotrauma
October 2022
Department of Neurosurgery, Trauma and Burns Center, University of Tunis-El Manar, Faculty of Medicine of Tunis,Ben Arous, Tunisia.
Bilateral epidural hematoma is a rare presentation in head trauma injuries, accounting for only 1%-2% of all epidural hematomas, but with a higher mortality rate than the unilateral form. Herein, we report the case of a 27-year-old man admitted to our department following a road traffic accident. On admission,his Glasgow Coma Scale (GCS) score was 13/15.
View Article and Find Full Text PDFAnisocoria after scopolamine transdermal patch contamination: A case report.
Medicine (Baltimore)
November 2021
Department of Ophthalmology, Kyung Hee University Hospital at Gangdong, Seoul, Korea.
Rationale: We report a case of anisocoria that occurred after contamination with a scopolamine transdermal patch, and introduce a diagnostic approach for anisocoria patients.
Patient Concerns: A 35-year-old woman with no past ophthalmologic history presented to the ophthalmology department complaining of a dilated pupil in the right eye. Corrected visual acuities was 20/20 in both eyes, and the intraocular pressures were 20 and 18 mm Hg in the right and left eye, respectively.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!