Purpose Of Review: Laryngeal framework surgery (LFS) is an indispensable surgical approach for the treatment of voice problems. The purpose of this review is to single out some relevant articles published on the topic of LFS from 2015 to mid-2016. Articles referring to injection laryngoplasty (augmentation) are entirely left aside.
Recent Findings: In the vast majority of recent publications, LFS mostly addresses surgery intended to improve vocal function in cases of glottic insufficiency. Here, medialization laryngoplasties remain the most important surgery. Arytenoid adduction remains an important technique within this field. Some clinical studies concerning indications and outcome of LFS are covered in the recent articles, trying to improve decision making for the indication of medialization laryngoplasty to enhance the rate of favorable long-term results. As in the past years, only a few articles report on laboratory research and other aspects of LFS.
Summary: Articles published from 2015 to mid-2016 show that further improvements in LFS have been made, both surgically-technically and in respect of patient selection. There is still a debate about the combination of medialization laryngoplasty and arytenoid adduction in patients with unilateral vocal fold paralysis or paresis (UVFP). Although augmentation laryngoplasties are significantly increasing in number, it seems that LFS remains an important procedure within phonosurgery.
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http://dx.doi.org/10.1097/MOO.0000000000000308 | DOI Listing |
Int J Mol Sci
December 2024
Research Unit of Biomedicine and Internal Medicine, University of Oulu, 902 20 Oulu, Finland.
Mucins 5AC (MUC5AC) and 5B (MUC5B) are the major mucins providing the organizing framework for the airway's mucus gel. We retrieved bronchial mucosal biopsies and bronchial wash (BW) samples through bronchoscopy from patients with chronic obstructive pulmonary disease ( = 38), healthy never-smokers ( = 40), and smokers with normal lung function ( = 40). The expression of MUC5AC and MUC5B was assessed immunohistochemically.
View Article and Find Full Text PDFInt J Lang Commun Disord
December 2024
Hearing, Speech & Language Center, Sheba Medical Center, Tel Hashomer, Israel.
Background: Head and neck cancer (HNC) is amongst the 10 most common cancers worldwide and has a major effect on patients' quality of life. Given the complexity of this unique group of patients, a multidisciplinary team approach is preferable. Amongst the debilitating sequels of HNC and/or its treatment, swallowing, speech and voice impairments are prevalent and require the involvement of speech-language pathologists (SLPs).
View Article and Find Full Text PDFFront Oncol
December 2024
Institute for Head and Neck Studies and Education, University of Birmingham, Birmingham, United Kingdom.
Background: The limitations of the traditional TNM system have spurred interest in multivariable models for personalized prognostication in laryngeal and hypopharyngeal cancers (LSCC/HPSCC). However, the performance of these models depends on the quality of data and modelling methodology, affecting their potential for clinical adoption. This systematic review and meta-analysis (SR-MA) evaluated clinical predictive models (CPMs) for recurrence and survival in treated LSCC/HPSCC.
View Article and Find Full Text PDFInt J Lang Commun Disord
December 2024
University of Liverpool & Liverpool Head and Neck Centre, Liverpool, UK.
Background: Over 200,000 patients are referred onto the suspected head and neck cancer (HNC) pathway annually in the UK, with around 3% receiving a cancer diagnosis. With new HNC advancements in identifying patients at low risk of a cancer diagnosis, one proposal is a speech and language therapy (SLT)-led first point of contact clinic for low-risk patients presenting with voice or swallowing symptoms.
Aims: To explore ear, nose and throat (ENT) surgeons' views regarding this model.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
December 2024
Voice is a vital tool for human communication, and its health spans across various stages of an individual's life cycle. This article discuss the importance of voice health from a lifecycle perspective, exploring the needs of voice, phonatory organ changes, the main etiologies and their incidence, the impact on social function, and treatment of voice disorders at different stages (childhood, adolescence, adulthood, and old age). During childhood, due to incomplete vocal cords development and weak behavioral control, the incidence of voice disorders is high, which adversely affects children's psychological and social function development.
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