Autoimmune swallowing disorders.

Curr Opin Otolaryngol Head Neck Surg

aMclaren Oakland Hospital, Pontiac bMichigan State University College of Osteopathic Medicine, East Lansing cMichigan State University, East Lansing dSt. John Macomb Hospital, Madison Heights eOakland University William Beaumont School of Medicine, Rochester fLakeshore Professional Voice Center, St. Clair Shores, Michigan, USA.

Published: December 2016

Purpose Of Review: Dysphagia can be the presenting symptom of autoimmune disease. The otolaryngologist should be familiar with and consider these disorders when assessing the patient with swallowing difficulties.

Recent Findings: The present review gives a brief overview of Sjogren's syndrome, granulomatosis with polyangiitis, pemphigus and pemphigoid, rheumatoid arthritis, systemic lupus erythematosus, scleroderma and inflammatory myopathies, and how they affect swallowing. Diagnosis of these diseases is generally based off of clinical presentation, serology, and/or biopsy. Corticosteroids in combination with other immune modulators and symptomatic therapy are the mainstays of treatment. Treatment should be coordinated with a rheumatologist.

Summary: The otolaryngologist should be able to recognize when a systemic disease may be the cause of a patient's dysphagia and guide appropriate evaluation. Furthermore, the otolaryngologist can help localize the specific nature of the swallowing problem and guide or provide treatment.

Download full-text PDF

Source
http://dx.doi.org/10.1097/MOO.0000000000000312DOI Listing

Publication Analysis

Top Keywords

autoimmune swallowing
4
swallowing disorders
4
disorders purpose
4
purpose review
4
review dysphagia
4
dysphagia presenting
4
presenting symptom
4
symptom autoimmune
4
autoimmune disease
4
disease otolaryngologist
4

Similar Publications

Background: Immune-mediated necrotizing myopathy (IMNM) is a type of autoimmune myositis. Anti-signal recognition particle (SRP) antibodies are highly specific to this disease.

Case: A 76-year-old woman presented with a 4-month history of acute progressive limb muscle weakness and dysphagia.

View Article and Find Full Text PDF

Autoimmune bullous diseases (AIBDs) are a group of conditions marked by the formation of blisters and erosions on the skin and mucous membranes. It occurs in all age groups, slightly more often affecting women. Several factors may be linked to the development of AIBDs, with nutrition being one of them.

View Article and Find Full Text PDF

Contactin-associated protein () gene mutations have been reported in cases of congenital hypomyelinating neuropathy (CHN), a rare hereditary neuropathy. We present a case of a term male infant born at 39 weeks 4 days with respiratory distress, impaired swallow function, and hypotonia. Neurological workup for structural, autoimmune, neuromuscular, and metabolic etiologies was negative and whole exome sequencing revealed a novel mutation in the gene, consistent with a diagnosis of CHN3.

View Article and Find Full Text PDF

Background: Guillain-Barré syndrome (GBS) is a rare autoimmune disease that affects the peripheral nervous system. It is characterized by the destruction of nerves involved in movement. This condition can lead to transient pain, changes in temperature and touch sensations, muscle weakness, loss of sensation in the legs and/or arms, and difficulty swallowing or breathing.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!