Medical directors may be asked to analyze their company's experienced laboratory results. This practical research note uses the example of trying to help predict the distribution of proposed insured's under a new preferred risk program as a way to illustrate how to marshal a company's lab results into a suitable dataset for analysis.
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http://dx.doi.org/10.17849/insm-45-02-098-102.1 | DOI Listing |
Mater Horiz
January 2025
College of Materials Science & Engineering, Zhejiang University of Technology, Hangzhou 310014, P. R. China.
Developing hydrogels with high conductivity and toughness a facile strategy is important yet challenging. Herein, we proposed a new strategy to develop conductive hydrogels by growing metal dendrites. Water-soluble Sn ions were soaked into the gel and then converted to Sn dendrites an electrochemical reaction; the excessive Sn ions were finally removed by water dialysis, accompanied by dramatic shrinkage of the gel.
View Article and Find Full Text PDFJ Colloid Interface Sci
January 2025
The Education Ministry Key Lab of Resource Chemistry, Joint International Research Laboratory of Resource Chemistry, Ministry of Education, Shanghai Frontiers Science Center of Biomimetic Catalysis, and Shanghai Key Laboratory of Rare Earth Functional Materials, College of Chemistry and Materials Science, Shanghai Normal University, Shanghai 200234 China. Electronic address:
A gold-cerium bimetallic asteroid nanoplatform (CeO@GNSs/Myr-HA) was obtained by electrostatically adsorbing ultra-small cerium dioxide (CeO) onto gold nanostars (GNSs) and further loading myricetin (Myr) and hyaluronic acid (HA). This nanoplatform exhibited three types of enzymatic properties-that is, GOD (glucose-oxidase), POD (peroxidase) and GSH-Ox (glutathione oxidase) mimicking catalytic activities. These enzymatic properties work together to effectively induce apoptosis in tumor cells.
View Article and Find Full Text PDFAnal Chem
January 2025
School of Life Sciences, Key Laboratory of Space Bioscience & Biotechnology, Northwestern Polytechnical University, Xi'an 710072, China.
Lymphoma is a malignant cancer characterized by a rapidly increasing incidence, complex etiology, and lack of obvious early symptoms. Efficient theranostics of lymphoma is of great significance in improving patient outcomes, empowering informed decision-making, and driving medical innovation. Herein, we developed a multifunctional nanoplatform for precise optical imaging and therapy of lymphoma based on a new photosensitizer (1-oxo-1-benzoo[de]anthracene-2,3-dicarbonitrile-triphenylamine (OBADC-TPA)).
View Article and Find Full Text PDFMicroorganisms
January 2025
Institute of Food Sciences, Shanxi Normal University, Taiyuan 030031, China.
Lactic acid Bacteria (LAB) convert tryptophan to indole derivatives and induce protective IL-22 production in vivo. However, differences in metabolizing capabilities among LAB species have not been widely investigated. In the present study, we compared the capabilities of 186 LAB strains to produce four kinds of indole derivatives, including indole-3-carboxaldehyde (IAId), indole-3-lactic acid (ILA), indole-3-propanoic acid (IPA), and indole-3-acetic acid (IAA).
View Article and Find Full Text PDFBiosensors (Basel)
January 2025
CBQF-Centro de Biotecnologia e Química Fina, Laboratório Associado, Universidade Católica Portuguesa, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.
Chronic Kidney Disease (CKD) is a disorder that affects over 10% of the global population, and that would benefit from innovative methodologies that would provide early detection. Since it has been reported that there are high levels of urease in CKD patients' saliva, this sample is a promising non-invasive alternative to blood for CKD detection and monitoring. This work introduces a novel 3D µPAD for quantifying urease activity in saliva in a range of 0.
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