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Myocardial micro-biopsy procedure for molecular characterization with increased precision and reduced trauma.
Sci Rep
May 2020
Department of Clinical Neuroscience, Karolinska Institutet, Solna, Sweden.
Endomyocardial biopsy is a valuable tool in cardiac diagnostics but is limited by low diagnostic yield and significant complication risks. Meanwhile, recent developments in transcriptomic and proteomic technologies promise a wealth of biological data from minimal tissue samples. To take advantage of the minimal tissue amount needed for molecular analyses, we have developed a sub-millimeter endovascular biopsy device, considerably smaller than current clinical equipment, and devised a low-input RNA-sequencing protocol for analyzing small tissue samples.
View Article and Find Full Text PDFUsefulness of micro-biopsy in the follow-up of oral lichen planus.
Minerva Stomatol
October 2016
Department of Dentistry, San Raffaele Hospital and Institute for Scientific Research, Vita-Salute San Raffaele University, Milan, Italy -
[Ductal carcinomas in situ].
Presse Med
January 2003
Anatomopathologie, Centre des Maladies du Sein, Oncologie Médicale, Hôpital Saint Louis, Paris. .
Epidemiology: Presently representing 15 to 30% of new cases of breast cancer, ductal carcinomas in situ do not have specific epidemiological characteristics. The age at which they occur is between 49 and 54 years.
Diagnostic Methods: The diagnosis is evoked primarily when confronted with an area of micro-calcifications discovered on a mammography.
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