Efficacy of treatments with toltrazuril 7.5% and lasalocid sodium in sheep naturally infected with Eimeria spp.

Rev Bras Parasitol Vet

Laboratório de Parasitologia Animal, Centro de Ciências Biológicas e da Saúde, Universidade Federal de Mato Grosso do Sul - UFMS, Campo Grande, MS, Brasil.

Published: May 2018

The objective of this study was to evaluate the efficacy of an experimental formulation of toltrazuril 7.5% + Trimix™ on a naturally acquired infection of Eimeria spp. in suckling lambs kept on pasture and, in another trial, evaluate the comparative efficacy between lasalocid and toltrazuril 7.5% + Trimix™ in newly weaned sheep under feedlot conditions that had been naturally infected with Eimeria spp. In the first experiment, 30 suckling lambs were divided into two groups: A - treated with toltrazuril 7.5% + Trimix™ and B- control. In experiment 2, 30 weaned sheep were divided into three groups: I - treated with toltrazuril 7.5% + Trimix™, II - treated with lasalocid and III - control. Treatment group A showed an efficacy of 90, 99.4 and 87.3% on days 5, 10 and 20, respectively. Treatment group I had an efficacy of 98.2, 92.6 and 94.5%, while group II had an efficacy of 72.7, 81.6 and 95.9% on days 7, 21 and 42, respectively. Eight Eimeria species were identified; E. ovinoidalis was the most common. Treatment with the toltrazuril 7.5% +Trimix ™ formulation was effective against Eimeria spp. in suckling lambs in field conditions and lambs weaned in under feedlot conditions.

Download full-text PDF

Source
http://dx.doi.org/10.1590/S1984-29612016048DOI Listing

Publication Analysis

Top Keywords

toltrazuril 75%
24
eimeria spp
16
75% trimix™
16
suckling lambs
12
group efficacy
12
naturally infected
8
infected eimeria
8
spp suckling
8
weaned sheep
8
feedlot conditions
8

Similar Publications

Background: Avian coccidiosis is considered among the infectious disease of high cost in the poultry industry. Herbal extracts are safe and reliable substitute anticoccidial drugs for chemical feed additives as they do not sequel to drug resistance and tissue remnants.

Objective: The current study aimed to assess the anticoccidial effect of an herbal complex of 3 plants (, , and ) in broiler chickens compared to toltrazuril anticoccidial.

View Article and Find Full Text PDF

Cystoisospora suis infection in suckling piglets in Brazil: Prevalence and associated factors.

Vet Parasitol Reg Stud Reports

November 2022

Department of Epidemiology, Bio-informatics and Animal Models, Wageningen Bioveterinary Research, Houtribweg 39, 8221 RA Lelystad, the Netherlands.

Piglet coccidiosis is a parasitic disease caused by the protozoan Cystoisospora suis, which is regarded as the most prevalent gastrointestinal parasite in intensive pig farms. Despite the availability of highly effective chemo-metaphylaxis (toltrazuril), coccidiosis is still prevalent in European and other countries. We conducted a cross-sectional study on swine farms in Brazil, to assess the prevalence of Cystoisospora suis in fecal samples and determined the associated factors.

View Article and Find Full Text PDF

Background: Coccidiosis is a poultry disease that occurs worldwide and is caused by Eimeria species. The infection is associated with reduced feed efficiency, body weight gain, and egg production. This study aimed to investigate the current status of coccidiosis and anticoccidial resistance to anticoccidial drugs used as part of control strategies for this disease in Korean chicken farms.

View Article and Find Full Text PDF

Co-amorphous supersaturated drug delivery systems are emerging as an alternative strategy to improve the water solubility of BCS II drugs. Typically, the supersaturation and stability of co-amorphous systems largely depend on the type of employed co-former. This study aims to assess the potential for active metabolites of drugs as co-former in drug-drug co-amorphous formulations.

View Article and Find Full Text PDF

Efficiency of 5% toltrazuril in the metaphylactic treatment of coccidiosis in naturally infected and extensively reared beef calves.

Trop Anim Health Prod

May 2021

Parasitic Disease Laboratory (LADOPAR), Department of Preventive Veterinary Medicine, Federal University of Santa Maria (UFSM), Av. Roraima, 1000, Prédio 63C, 97015-000, Camobi, Santa Maria, RS, Brazil.

Eimeria spp. infection is one of the main diseases that affect young cattle in beef and dairy herds, leading to economic losses and compromising the performance and growth of animals. This study aimed to evaluate the effectiveness of different protocols of metaphylactic treatment with 5% toltrazuril (15 mg/kg) in naturally infected, extensively reared beef calves from birth to 1 year of age.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!