AI Article Synopsis
- A study was conducted to check for the presence of onconeural antibodies in 585 psychiatric inpatients, as these antibodies can be linked to neurological disorders with psychiatric symptoms.
- Out of all the tested samples, only one showed a positive result for the antirecoverin IgG antibody, indicating a very low prevalence of these antibodies in this patient group.
- The findings imply that onconeural antibody positivity is uncommon in acute psychiatric care settings, which has important clinical implications for diagnosing and treating psychiatric disorders.
Article Abstract
Paraneoplastic neurological disorders associated with onconeural antibodies often appear with neuropsychiatric symptoms. To study the prevalence of onconeural antibodies in patients admitted to acute psychiatric inpatient care, the serum of 585 such patients was tested for antibodies targeting MOG, GLRA1B, DPPX, GRM1, GRM5, DNER, Yo, ZIC4, GAD67, amphiphysin, CV2, Hu, Ri, Ma2, and recoverin. Only one sample was positive (antirecoverin IgG). The present findings suggest that serum onconeural antibody positivity is rare among patients acutely admitted for inpatient psychiatric care. The clinical implications of this finding are discussed.
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| http://dx.doi.org/10.1176/appi.neuropsych.16050110 | DOI Listing |
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