Purpose: Increasing evidence shows the detrimental impact of high physical work demands for cardiovascular health and mortality. The aim of this study was to investigate the buffering effects of social support at work and job control in the relation between physical work demands and incidence of coronary events.
Methods: The study included 14,337 middle-aged men free from coronary heart disease (CHD) at baseline. The sample consisted of a mixed occupational group recruited within 18 organizations from the manufacturing, service, and public sector. Data were collected through standardized questionnaires and clinical examinations. The incidence of clinical coronary events was monitored during a mean follow-up time of 3.15 years. Multilevel Cox proportional hazard regression modeling was used, adjusting for socio-demographic and classical coronary risk factors.
Results: Social support at work buffered the impact of physical work demands on CHD risk: Only among workers with low social support at work did physical work demands significantly increase the risk for CHD incidence (fully adjusted HR 2.50: 95 % CI 1.13-5.50), while this harmful effect completely disappeared in case of high level of workplace social support (fully adjusted HR 0.40; 95 % CI 0.09-1.70). No interaction or buffering effect with job control was observed.
Conclusions: The results of our study suggest that supportive relationships at work may be a useful resource for reducing the cardiovascular risk associated with physical work demands in men. Future studies are needed to confirm this moderating role of workplace social support and to unravel the underlying mechanisms.
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http://dx.doi.org/10.1007/s00420-016-1165-z | DOI Listing |
J Orthop Surg Res
December 2024
Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Background: Physical therapy (PT) is widely employed in osteoarthritis (OA). This study aimed to explore the research development of PT for OA and to identify the emerging treatment, and verify its efficacy.
Materials And Methods: The Web of Science Core Collection was used to conduct the bibliometric analysis.
Langmuir
December 2024
Key Laboratory of Functional Polymer Materials of Ministry of Education and College of Chemistry, Nankai University, Tianjin 300071, China.
Polyelectrolyte complex (PEC) hydrogels provide a promising strategy to develop a class of physically cross-linked networks characterized by exceptional toughness and self-healing properties. However, the precise control of the microstructure and the enhancement of mechanical properties still pose challenges in the field of PEC hydrogels. Herein, we propose a strategy to manipulate the structure of PEC with competitively charged surfactant micelles, leveraging the spatially confined surface charge and excluded volume effects to overcome coacervation issues associated with the PEC, thus achieving a simple one-step preparation of macroscopically uniform and tough PEC hydrogels.
View Article and Find Full Text PDFBrain Res
December 2024
Federal University of São Paulo, Paulista School of Medicine, Department of Physiology, Laboratory of Neurophysiology, São Paulo, Brazil.
Alzheimer's disease is a progressive neurodegenerative disease affecting memory, language, and thinking with no curative treatment. Symptoms appear gradually, and pathological brain changes may occur twenty years before the physical and psychological signs, pointing to the urgent development of preventive interventions. Physical activity has been investigated as a preventive tool to defeat the main biological features of AD: pathological amyloid protein plaques, tau tangles, myelin degeneration, and iron deposits in the brain.
View Article and Find Full Text PDFBioresour Technol
December 2024
CAS Key Laboratory of High Magnetic Field and Iron Beam Physical Biology, Institute of Intelligent Machines, Hefei Institute of Physical Sciences, Chinese Academy of Sciences, Hefei 230031, China; Science Island Branch of Graduate School, University of Science and Technology of China, Hefei 230026, China. Electronic address:
Low-temperature plasma (LTP) has gained significant attention recently due to its unique properties and potentially wide applications in agriculture, pharmaceuticals, medicine, cosmetics, and the food industries. Microalgae have become important to human life since they provide raw materials and bioactive products to industries. This review especially examines how LTP technology can be utilized to enhance microalgae growth and production of various metabolites and bioactive compounds such as astaxanthin, biofuel, lipid, protein, and polysaccharides through mutagenesis and/or stimulation ways, and suggests that LTP may be combined with multi-omics tools such as proteomics, transcriptome, metabolomics and advanced methods such as single-cell analysis techniques to provide a promising strategy for acquiring desirable strains in algal mutant breeding and for enhancing the production of bioactive compounds in the microalgae.
View Article and Find Full Text PDFBioresour Technol
December 2024
Sanya Institute of Nanjing Agricultural University, Department of Microbiology, Key Lab of Microbiological Engineering of Agricultural Environment, Ministry of Agriculture, College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, PR China. Electronic address:
High production cost of cellulases limits its commercial application on lignocellulose. Solid-state fermentation (SSF) has special advantages of water and energy conservation, however, the lack of free water and water loss during fermentation limits its application. In this paper, a constructed water-supply SSF was used to improve carboxymethyl cellulose activity and filter paper activity of 1.
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