Surgical manipulation of corneal shape requires an accurate and precise method of measuring anterior corneal curvature from apex to limbus. We evaluated the accuracy and precision of the Bausch & Lomb Keratometer, Kera Corneascope, and Computed Anatomy Corneal Modeling System by measuring comparable locations on four calibrated steel test balls. The Keratometer and Corneal Modeling System were more accurate and precise than the Corneascope. No statistically significant difference was found between the Keratometer and Corneal Modeling System with respect to accuracy or precision. In addition, the accuracy and precision of all 31 rings of the Corneal Modeling System were studied. Rings 2 through 26 were read accurately and precisely within +/- 0.25 diopter on three of the four balls. Values on the steepest ball were within +/- 0.37 diopter.
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http://dx.doi.org/10.1001/archopht.1989.01070020301043 | DOI Listing |
Int J Med Robot
February 2025
Faculty of Health, Education, Medicine and Social Care, Medical Technology Research Centre, The Institute of Excellence in Robotic Surgery, Anglia Ruskin University, Chelmsford, UK.
Background: The human eye consists of highly sensitive, hydrated, and relatively thin tissues, making precise control and accurate force estimation crucial in robotic eye surgery. This paper introduces a novel control method and state observer designed for a gripper surgical instrument used on the external ocular surface during robotic eye surgery.
Methods: A novel state observer, operating in tandem with the controller, estimates the applied force.
Eye Vis (Lond)
January 2025
National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, China.
Background: Keratoconus (KC) is a prevalent corneal condition with a modest genetic basis. Recent studies have reported significant genetic associations in multi-ethnic cohorts. However, the situation in the Chinese population remains unknown.
View Article and Find Full Text PDFBull Exp Biol Med
January 2025
Hunan University of Chinese Medicine, Changsha, Hunan, China.
We studied the effect of acteoside on a model of human corneal epithelial cells (HCEC) injury induced by HO. HCEC were divided into 4 groups and cultured for 24 h in normal medium (intact and control groups, respectively), or in a medium containing DMSO or 160 μM acteoside (DMSO and acteoside groups, respectively). Then, HO solution was added to HCEC for 4 h, except for intact cells.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
January 2025
Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital of Fudan University, Shanghai, China.
Purpose: R-spondin3 (RSPO3), a mammalian-specific amplifier of WNT signaling pathway, maintains the homeostasis of various adult stem cells. However, its expression at the limbus and the effect on limbal epithelial stem cells (LESCs) remains unclear. We investigated the impact of RSPO3 on the proliferation and self-renewal of LESCs and explored its molecular mechanisms.
View Article and Find Full Text PDFOphthalmol Glaucoma
January 2025
Glaucoma Division, Stein Eye Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California. Electronic address:
Purpose: Investigate the influence of baseline blood pressure (BP) on retinal nerve fiber layer (RNFL) rates of change (RoC) in glaucoma patients with central damage or moderate to severe disease.
Design: Prospective cohort study.
Participants: 110 eyes with ≥4 RNFL optical coherence tomography scans and ≥2 years of follow-up.
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