The development of a useful methodology for simple, scalable, and transformative automation of oligosaccharide synthesis that easily interfaces with existing methods is reported. The automated synthesis can now be performed using accessible equipment where the reactants and reagents are delivered by the pump or the autosampler and the reactions can be monitored by the UV detector. The HPLC-based platform for automation is easy to setup and adapt to different systems and targets.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496006 | PMC |
| http://dx.doi.org/10.1021/acs.joc.6b01439 | DOI Listing |
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