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Physical function after extracorporeal membrane oxygenation in patients pre or post heart transplantation - An observational study. | LitMetric

Physical function after extracorporeal membrane oxygenation in patients pre or post heart transplantation - An observational study.

Heart Lung

Department of Physiotherapy, The Alfred Hospital, 55 Commercial Road, Melbourne, Victoria, 3181, Australia; Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, Monash University, 99 Commercial Road, Melbourne, 3004, Australia.

Published: May 2017

Objective: To describe physical function, leg complications and health-related quality of life (HRQOL) in the three months following extracorporeal membrane oxygenation (ECMO) pre- or post-heart transplantation (HTx).

Background: Little is known about functional recovery following ECMO before or after HTx.

Methods: A 2-year retrospective study in patients who received ECMO pre or post HTx. Strength, mobility, leg complications and HRQOL were recorded to hospital discharge. Six-minute walk distance (6MWD) was assessed at hospital discharge and 3 months.

Results: 25 patients were included, with 80% (20/25) survival to hospital discharge. At ICU discharge, strength and mobility were poor but improved by hospital discharge (p < 0.001) despite leg complications in 44% (11/25) of patients. The 6MWD improved over time (mean 203 m, 95% confidence interval 140-265). HRQOL scores were lower than Australian norms (p < 0.05).

Conclusion: Patients requiring ECMO pre or post HTx had impaired physical function at ICU discharge and leg complications were common.

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Source
http://dx.doi.org/10.1016/j.hrtlng.2016.07.007DOI Listing

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