The use of a positive-displacement needleless intravenous access device was associated with lower microbial contamination rates compared with a neutral-displacement device when used on central venous catheters in hemato-oncology patients. In addition, rates of central line-associated bloodstream infection did not differ when either device was used.
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http://dx.doi.org/10.1016/j.ajic.2016.06.027 | DOI Listing |
J Infus Nurs
November 2024
Author Affiliations: Department of Nursing Methodology, Quality and Research (Terradas Roblado, Lacueva Perez) and Home Hospitalization Department (Estevez Estevez), Hospital del Mar (Lafuente Cabrero, Civit Cuñado, García Sardelli, Molina Huerta), Barcelona, Spain; Department of Public Health, Mental Health and Maternal and Child Health Nursing (Esquinas) and Department of Basic Nursing (Tortosa), Faculty of Nursing, University of Barcelona, Spain.
Home intravenous antibiotic treatment (HIAT) consists of the administration of intravenous antibiotic therapy in the home of the patient. Short peripheral intravenous catheters have long been the first option for antimicrobial therapies. However, these devices are known for their short durability.
View Article and Find Full Text PDFCureus
June 2024
Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, USA.
Introduction Peripheral intravenous (IV) administration sets are a source of infection that increases morbidity, mortality, and healthcare costs. In this quality improvement project, we aimed to enhance compliance with peripheral IV hub disinfection at anesthesia induction to follow the American Society of Anesthesiologists (ASA) safe medication injection guidelines. Methods This study was conducted in the main operating suite of the University of Miami's principal hospital between June and October 2023.
View Article and Find Full Text PDFAnaesth Intensive Care
May 2024
Department of Anesthesiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
SummaryA vascular introducer sheath is often used for rapid volume replacement. However, common manipulations such as the addition of needleless connectors to infusion ports and the insertion of catheters or other devices through the introducer sheath may impede flow. In this study we utilised a rapid infuser to deliver room-temperature normal saline through two introducer sheath configurations with and without the addition of needleless connectors and the placement of catheters through the introducer sheaths.
View Article and Find Full Text PDFNat Commun
January 2024
Institute of Functional Nano & Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science and Technology, Jiangsu Key Laboratory for Carbon-based Functional Materials and Devices, Soochow University, Suzhou, 215123, China.
Transdermal drug delivery has been regarded as an alternative to oral delivery and subcutaneous injection. However, needleless transdermal delivery of biomacromolecules remains a challenge. Herein, a transdermal delivery platform based on biocompatible fluorocarbon modified chitosan (FCS) is developed to achieve highly efficient non-invasive delivery of biomacromolecules including antibodies and antigens.
View Article and Find Full Text PDFMethodsX
December 2023
Department of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY 14203, USA.
Rat intravenous self-administration is a widely-used animal model in the study of substance use disorders. Rats are tethered to a drug delivery system usually through a port or button that interfaces the drug delivery system with a chronic indwelling jugular vein catheter. These buttons can be purchased commercially but are costly, presenting a significant economic barrier for many researchers.
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