The authors analyze the morbidity with temporary loss of working capacity due to diseases of the digestive organs in workers realizing technological explosions in the ore-mining and processing industry. The etiological role is shown of trinitrotoluene in the formation of really high levels of morbidity of the digestive organs.
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Sci Rep
January 2025
Department of Rehabilitation Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200336, China.
Accurately extracting organs from medical images provides radiologist with more comprehensive evidences to clinical diagnose, which offers up a higher accuracy and efficiency. However, the key to achieving accurate segmentation lies in abundant clues for contour distinction, which has a high demand for the network architecture design and its practical training status. To this end, we design auxiliary and refined constraints to optimize the energy function by supplying additional guidance in training procedure, thus promoting model's ability to capture information.
View Article and Find Full Text PDFJ Invertebr Pathol
January 2025
Instituto de Investigaciones en Producción Sanidad y Ambiente (IIPROSAM), CONICET-Universidad Nacional de Mar del Plata, Centro de Asociación Simple CIC-PBA, Juan B. Justo 2550, 7600 Mar del Plata, Buenos Aires Province, Argentina.
Pomacea canaliculata is a highly successful invasive snail that shapes freshwater communities in both native and invaded habitats. We studied its digenean parasites from three freshwater bodies in its native distribution area in Buenos Aires Province, Argentina. An integrated approach was used to determine and describe the larval stages of digenean, including morphological, molecular, and histopathology analyses.
View Article and Find Full Text PDFPLoS One
January 2025
Laboratory of Hepato-Gastroenterology, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium.
The emerging field of 3D organ modeling encounters several imaging issues in particular related to antigen retrieval and sample loss during staining processes. Due to their compact shape, several antibodies fail to penetrate intact organoids or spheroids. Histology of organoids can be approached by paraffin inclusion and sectioning at 5 μm as performed for biopsies.
View Article and Find Full Text PDFJAMA Surg
January 2025
Population Health Research Institute, Hamilton, Ontario, Canada.
Importance: Perioperative bleeding is common in general surgery. The POISE-3 (Perioperative Ischemic Evaluation-3) trial demonstrated efficacy of prophylactic tranexamic acid (TXA) compared with placebo in preventing major bleeding without increasing vascular outcomes in noncardiac surgery.
Objective: To determine the safety and efficacy of prophylactic TXA, specifically in general surgery.
Methods Mol Biol
January 2025
Biomic Auth, Bioanalysis and Omics Laboratory, Centre for Interdisciplinary Research of Aristotle, University of Thessaloniki, Innovation Area of Thessaloniki, Thermi, Greece.
The gut's symbiome, a hidden metabolic organ, has gained scientific interest for its crucial role in human health. Acting as a biochemical factory, the gut microbiome produces numerous small molecules that significantly impact host metabolism. Metabolic profiling facilitates the exploration of its influence on human health and disease through the symbiotic relationship.
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