AI Article Synopsis
- A retrospective cohort study compared the outcomes of patients undergoing cardiac surgery who received etomidate versus those who received other induction agents.
- The study, involving nearly 9,000 patients, found no significant difference in the incidence of postoperative atrial arrhythmia or the duration of intensive care and hospital stay between the two groups.
- However, patients who received etomidate did require significantly more packed red blood cells post-surgery, but overall, complications were similar across both groups.
Article Abstract
Objective: To compare incidence of atrial arrhythmia, duration of care, and major complications after cardiac surgery between patients who received etomidate and those who received other induction agents.
Design: Retrospective cohort study utilizing propensity score matching.
Setting: A single academic, tertiary care hospital.
Participants: Eight thousand nine hundred seventy-eight patients undergoing coronary artery bypass grafting (CABG), valve, or combined valve/CABG surgery requiring cardiopulmonary bypass between January 2005 and December 2010.
Interventions: Patients were divided into those who received etomidate at anesthetic induction and those who received another induction agent. Patients given etomidate were propensity-score matched to patients given other induction agents in a 2:1 ratio.
Measurements And Main Results: Of 8,978 patients who underwent CABG, valve, or combined valve/surgery, 6,313 received etomidate and 2,665 received other induction agents. Among these, the authors successfully matched 4,094 etomidate patients with 2,524 non-etomidate patients. The authors did not find a significant association between receiving etomidate and odds of experiencing postoperative atrial arrhythmia (odds ratio [98.3% confidence interval] of 1.07 [0.92, 1.23], p = 0.29). Etomidate was not associated significantly with either intensive care unit or hospital stay. Etomidate was associated significantly with use of packed red blood cells (odds ratio [99.6% confidence interval] of 1.32 [1.02, 1.70], p = 0.002), but not with use of fresh frozen plasma, platelets, or cryoprecipitate. None of the other complications differed significantly between the groups.
Conclusions: Etomidate was not associated with increased incidence of postoperative atrial arrhythmia or increased intensive care unit or hospital stay.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1053/j.jvca.2016.04.022 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Atrial Fibrillation in Patients with Breast Cancer: A Literature Review.
Cardiol Ther
December 2024
Cardio-Oncology Program, Division of Cardiovascular Medicine, Department of Medicine, Lahey Hospital and Medical Center, 41 Mall Road, Burlington, MA, 01805, USA.
In addition to traditional risk factors, patients with breast cancer are at an increased risk of atrial fibrillation due to cancer itself and certain cancer therapies. Atrial fibrillation in these patients adds to their morbidity and mortality. The precise mechanisms leading to the increased atrial fibrillation in patients with breast cancer are not well understood.
View Article and Find Full Text PDFDigital Devices for Arrhythmia Detection: What Is Still Missing?
Clin Cardiol
January 2025
Second Department of Internal Medicine, University of Toyama, Toyama, Toyama, Japan.
Right atrial reverse remodeling and risk of atrial arrhythmias after surgical pulmonary valve replacement.
Int J Cardiol Congenit Heart Dis
March 2024
From the Department of Cardiovascular Medicine, Mayo Clinic Rochester, MN, 55905, USA.
Background: Right atrial (RA) dysfunction and atrial arrhythmias are relatively common in adults with repaired tetralogy of Fallot. The purpose of this study was to determine whether RA function improved after surgical pulmonary valve replacement (PVR), and the association between postoperative RA reverse remodeling and late postoperative atrial arrhythmias.
Method: RA reverse remodeling (ΔRA reservoir strain based speckle tracking echocardiography) was calculated as: ([postoperative RA reservoir strain - preoperative RA reservoir strain]/preoperative RA reservoir strain)x100.
Atrial arrhythmia predicts late events and mortality in patients with D-transposition of the great arteries and atrial switch repair.
Int J Cardiol Congenit Heart Dis
March 2024
Department of Cardiovascular Diseases, Mayo Clinic, Jacksonville, FL, USA.
Aims: Patients with D-transposition of the great arteries (D-TGA) and atrial switch experience late morbidity and mortality related to atrial arrhythmias and systemic right ventricular (SRV) failure. We sought to analyze the influence of atrial arrhythmias on long-term outcomes in this group.
Methods: A retrospective review of all patients with D-TGA and atrial switch followed at a tertiary care center was performed.
A new strategy for monitoring of direct oral anticoagulants in patients with cyanotic and complex congenital heart disease.
Int J Cardiol Congenit Heart Dis
December 2024
Service of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Background: Patients with congenital heart disease (CHD) often require an oral anticoagulation. Vitamin K antagonists (VKA) are the standard treatment, however, an increased hematocrit in patients with secondary erythrocytosis due to cyanosis complicates the correct measurement of the international normalized ratio. Direct oral anticoagulants (DOAC) could be an alternative, but data on their efficacy and safety in complex and cyanotic CHD patients are scarce.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!