The complicated course of meningococcal infection is distinguished by a long-term increase in the level of aspartate transferase and creatine phosphokinase. There were three types of changes in the activity of creatine phosphokinase, while changes in the activity of aspartate transferase were not so diverse. Patients had isolated as well as combined increase in the activity of both these enzymes. Lipid peroxidation was also augmented which corresponded to changes in the level of aspartate transferase. The high level of enzymes in the blood in meningococcal infection is the result of cytolysis as well as myocardial hyperfunction in the acute period of the disease.
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