Objectives: Aging entails deterioration in sensory, physical, and cognitive functions, raising doubt in the driving capacity of older drivers, especially when the deficits are severe, as in dementia. Many older drivers, especially women, adapt their driving habits in order to compensate for these deficits and eventually stop driving. The present prospective study assessed driving cessation in men and women throughout the dementia process, including a 2-year pre-dementia phase.
Methods: The study was based on a three-city cohort of subjects who were aged 65 years and older in 2000 and followed for more than 10 years. Active dementia detection was conducted at each follow-up. The probability of driving cessation was assessed in men and women during the 2-year pre-dementia phase and until 5 years after diagnosis.
Results: In the 2-year pre-dementia phase, both men and women ceased driving earlier than drivers with no central nervous system pathology (p < 0,001), and women ceased driving earlier than men. A total of 45% of men and 74% of women had already ceased driving at dementia diagnosis. In contrast, the probability of cessation within 3 years after diagnosis was similar between men and women.
Conclusion: The study showed that, in this French urban population, few demented drivers, especially women, were still driving after diagnosis. Those who continued to drive 3 years after the diagnosis all had Alzheimer-type dementia. There is certainly a need for physicians to help these drivers to adapt their driving activity to their deficits and to prepare them to stop driving. Copyright © 2016 John Wiley & Sons, Ltd.
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http://dx.doi.org/10.1002/gps.4565 | DOI Listing |
PLoS One
January 2025
Department of Pediatrics, Copenhagen University Hospital-North Zealand, Hillerød, Denmark.
Background: Identification of mother-infant pairs predisposed to early cessation of exclusive breastfeeding is important for delivering targeted support. Machine learning techniques enable development of transparent prediction models that enhance clinical applicability. We aimed to develop and validate two models to predict cessation of exclusive breastfeeding within one month among infants born after 35 weeks gestation using machine learning techniques.
View Article and Find Full Text PDFJ Environ Manage
January 2025
School of Landscape Architecture, Beijing Forestry University, Beijing 100083, China. Electronic address:
Flow cessation leads to severe degradation of river corridor landscape structure, habitat quality, and ecological functions. This study focuses on the representative river with ceased flow in northern China, the Yongding River plain section. Utilizing long-term, high-resolution satellite remote sensing imagery and the InVEST model, we analyzed the spatiotemporal evolution of landscape structure and habitat quality (HQ) before and after river corridor flow cessation over the past 50 years.
View Article and Find Full Text PDFJ Biochem
January 2025
Division of Cancer and Senescence Biology, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa, Japan.
J Subst Use Addict Treat
December 2024
The University of Manchester, Manchester Centre for Health Psychology, Division of Psychology and Mental Health, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester, UK; Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.
Introduction: Smoking prevalence rates in prison are typically four times higher than the rates found within community-based settings, increasing premature mortality. Encouraging smokers to self-administer incentives contingent on abstinence (i.e.
View Article and Find Full Text PDFInt J Drug Policy
December 2024
School of Sociology, Philosophy and Anthropology, University of Exeter, UK. FF16, Byrne House, Streatham Drive, Exeter, EX4 4AP, UK. Electronic address:
Background: Existing research highlights an increase in psychedelic microdosing, particularly for therapeutic purposes and as a means for self-enhancement. However, we know little about the different routes into and out of microdosing, particularly by those who do not consume other illicit substances, and of the processes involved in the development, maintenance, and cessation of practices.
Methods: Drawing upon a trans-national interview-based study of 23 participants actively microdosing (n = 19), about to start (n = 3), or who were past users (n = 1), we develop a phased-based analysis of different user pathways.
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