AI Article Synopsis

  • A 63-year-old immunocompromised man developed a laryngeal mass due to viral infections, resulting in a life-threatening airway blockage requiring urgent intubation and mechanical ventilation.
  • Initial treatment with acyclovir for herpes zoster was changed to ganciclovir after finding a concurrent cytomegalovirus infection.
  • The patient's condition improved, and he was taken off the ventilator after 10 days, with imaging showing no signs of the mass, suggesting the combined viral infections likely contributed to the mass formation.

Article Abstract

Several viral infections may occasionally induce supraglottic mass lesions, resulting in an obstructive airway emergency. We herein report one such case in a 63-year-old male immunocompromised patient with nephrotic syndrome due to membranous nephropathy who also had ophthalmic herpes zoster with a laryngeal mass, which required urgent intubation and mechanical ventilation. The patient was initially treated with acyclovir; however, because a serological analysis revealed a concurrent cytomegalovirus infection, we discontinued the administration of acyclovir and gave priority to the simultaneous treatment of the cytomegalovirus and varicella-zoster virus infections with ganciclovir. The clinical course was favorable, and he was weaned from the ventilator 10 days later when a serial imaging analysis revealed no signs of the supraglottic mass, leading us to conclude that these two viral infections could have additively or synergistically contributed to the development of the local pseudotumor. The diagnostic and therapeutic concerns arising in the current case are also discussed.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978193PMC
http://dx.doi.org/10.4137/CCRep.S40058DOI Listing

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