AI Article Synopsis
- Addition of low concentrations of ascorbic acid (5-10 micrograms/ml) to chick embryo cultures sped up the fusion process of muscle cells significantly.
- At 30 hours, cultures with ascorbic acid showed fusion rates three times higher than the control group, but by 50 hours, the fusion rates were similar in both groups.
- The study found that adding ascorbic acid at 24 hours or in calcium-deprived conditions did not affect fusion, highlighting that ascorbic acid's interaction with calcium is crucial for enhancing myogenic fusion.
Article Abstract
Addition of low concentrations of ascorbic acid (5 micrograms/ml to 10 micrograms/ml) to myogenic chick embryo cultures resulted in an early fusion. At 30 h cultures receiving small amounts of ascorbic acid presented fusion rates 3 times that of the control. However, control rates of fusion were not different from those of experimentals at 50 h. No such effect was seen with ascorbic acid added at 24 h of culture, or with ascorbic acid addition to a calcium-deprived system. These findings demonstrate that the calcium binding properties of ascorbic acid can induce precocious myogenic fusion.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/BF02623631 | DOI Listing |
Publication Analysis
Top Keywords
ascorbic acid
24
ascorbic
6
fusion
5
acid
5
acid facilitates
4
facilitates chicken
4
chicken myoblast
4
myoblast fusion
4
fusion vitro
4
vitro addition
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!