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http://dx.doi.org/10.1159/000382038 | DOI Listing |
Pharmaceuticals (Basel)
December 2024
Department of Biomedical Engineering, School of Engineering Sciences, College of Basic & Applied Sciences, University of Ghana, Legon, Accra P.O. Box LG 77, Ghana.
: Pteridine reductase 1 (PTR1) has been one of the prime targets for discovering novel antileishmanial therapeutics in the fight against Leishmaniasis. This enzyme catalyzes the NADPH-dependent reduction of pterins to their tetrahydro forms. While chemotherapy remains the primary treatment, its effectiveness is constrained by drug resistance, unfavorable side effects, and substantial associated costs.
View Article and Find Full Text PDFInsects
January 2025
Protein Chemistry and Bioactive Peptides Laboratory, Purdue University, 745 Agriculture Mall, West Lafayette, IN 47907, USA.
Farmed edible insects are considered a potential resource to help address food security concerns toward the year 2050. The sustainability (e.g.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
January 2025
Obstetrics and Gynecology Departement, Medical Faculty of Andalas University, Padang, West Sumatera, Indonesia.
Background: Understanding fetal growth is essential for predicting perinatal outcomes and long-term health implications. This study explores the correlation between ultrasound parameters and gestational age in the Minangkabau ethnic group, focusing on the biometric variables biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), femur length (FL), and humerus length (HL) during the second trimester.
Methods: Conducted from December 2020 to December 2021, the research employed a cross-sectional design at the Fetomaternal clinic of Hospital M.
Vaccines (Basel)
January 2025
Kauno Kolegija Higher Education, Faculty of Medicine, Pramones pr 20, 50468 Kaunas, Lithuania.
Background: Hepatitis E virus (HEV) infection presents a significant health risk in endemic regions, especially for pregnant women, who face higher risks of severe complications, including maternal and fetal mortality. The recombinant HEV vaccine, HEV239, has demonstrated high efficacy in the general population, yet data on its safety and efficacy in women of a childbearing age remain limited. This systematic review and meta-analysis aim to evaluate the safety and effectiveness of HEV239 in this specific population, with a focus on pregnancy-related outcomes.
View Article and Find Full Text PDFFront Cardiovasc Med
January 2025
Hyperbaric Oxygen, Chengdu First People's Hospital, Chengdu, Sichuan, China.
Background And Purpose: The hemoglobin levels in the peripheral blood of individuals living at high altitudes are significantly higher than normal levels. These levels are closely associated with atherosclerosis and cardiovascular events. This study aimed to investigate the correlation between hemoglobin levels in the peripheral blood and hypertension in high-altitude regions, providing a basis for preventing and treating primary hypertension in these regions.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!