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Changes in DHEA-s levels during the first year of treatment in patients with clinical burnout are related to health development. | LitMetric

AI Article Synopsis

  • A study measured DHEA-S levels in 122 patients with clinical burnout over their first year of treatment to explore how these levels relate to health improvement.
  • About half of the patients showed an increase in DHEA-S levels, while the other half had decreased levels, but there was no initial difference in burnout symptoms or health status between the two groups.
  • Patients with increased DHEA-S levels reported greater reductions in burnout symptoms and better overall health, suggesting that changes in DHEA-S could indicate the potential for recovery in burnout patients.*

Article Abstract

The regenerative hormone DHEA-S was measured in 122 patients with clinical burnout during their first year of treatment. Relations between change of DHEA-S levels and development in health were investigated. About half of the patients exhibited increased DHEA-S levels during the year, while the other half exhibited decreased levels. There was no difference in burnout symptoms or associated health status at baseline between subsequent DHEA-S increasing and DHEA-S decreasing groups. Greater reduction in the burnout symptoms was observed in patients in who DHEA-S levels increased during the year, than in the patients in who DHEA-S levels decreased. Relative change of DHEA-S and direction of the change during the year both predicted burnout symptoms at the end of the year. In addition, patients with increased DHEA-S levels had better self-rated health, vitality and well-being. Our data suggest that changes in DHEA-S are associated with prognosis for the outcome in burnout patients.

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Source
http://dx.doi.org/10.1016/j.biopsycho.2016.08.003DOI Listing

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