Purpose: This study aimed to evaluate the clinical prognosis of diplopia and identify factors that are potentially predictive of residual diplopia postoperatively in pediatric patients with orbital blowout fracture.
Material And Methods: This was a retrospective study of clinical data from 135 children and adolescents less than 18 years of age who were diagnosed with orbital blowout fractures between January 2008 and June 2014 in the Department of Ophthalmology. A Kaplan-Meier curve and log-rank statistics were used to identify the recovery status from diplopia. Univariate and multivariate Cox proportional hazards analyses were conducted to identify the characteristics associated with residual diplopia.
Results: Recovery from diplopia was rapid and obvious within 1 year after surgical repair; nearly 80% of the patients were cured of diplopia at that time point, according to the curve. Approximately 85% of the patients would completely recover from diplopia over time, and the remaining patients would most likely have residual diplopia. Multivariate analysis demonstrated that patient age (p < 0.001), the time interval between injury and surgery (p < 0.001) and preoperative muscle swelling (p = 0.028) were factors predictive of residual diplopia.
Conclusion: Early intervention in pediatric patients with orbital blowout fracture is recommended to reduce the rate of residual diplopia. Swelling of the ocular muscle and younger age may result in a prolonged recovery time and a lower recovery rate from diplopia after surgery. The recovery from diplopia in pediatric patients appears to be stable 1 year after surgical repair. Therefore, a follow-up time of at least 1 year is recommended for an overall evaluation of residual diplopia in children.
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http://dx.doi.org/10.1016/j.jcms.2016.06.014 | DOI Listing |
Turk Arch Pediatr
January 2025
Pathology Unit, IRCCS Istituto Giannina Gaslini, Genova, Italy.
Introduction: Giant cell tumor of bone (GCTB) is a rare, typically benign neoplasm that primarily affects long bones in adults, with clival involvement being extremely rare, particularly in pediatric cases: a mini-review shows a total of 28 described cases, of which only 5 were truly pediatric (within 14 years of age). Surgery is the treatment of choice, and Denosumab is reported to be the most effective drug therapy. To date, the GCTB's molecular hallmark is the somatic mutation p.
View Article and Find Full Text PDFCureus
November 2024
Anesthesiology and Pain Medicine, Harborview Medical Center, Seattle, USA.
BMJ Case Rep
December 2024
Radiology Department, Queen Alexandra Hospital, Portsmouth, Hampshire, UK.
A woman in her 70s, with a background of mantle cell lymphoma (MCL), presented with headache and diplopia. Neuro-ophthalmic examination revealed a combination of Horner syndrome and ipsilateral pupil sparing oculomotor nerve palsy (ONP). Cerebrospinal fluid immunophenotyping demonstrated CD5 positive clonal B lymphocytes, consistent with neurological involvement by MCL.
View Article and Find Full Text PDFJ Pediatr Ophthalmol Strabismus
November 2024
The authors present the case of a 5-year-old boy who developed a unilateral internuclear ophthalmoplegia (INO) following mild head trauma with supporting magnetic resonance imaging (MRI) findings of damage to the medial longitudinal fasciculus. At 2 months of follow-up, the patient had resolution of diplopia and only minimal residual nystagmus. Although rare in the children, INO can develop following head trauma.
View Article and Find Full Text PDFAm J Ophthalmol
November 2024
From the State Key Laboratory of Ophthalmology (L.C., Y.S., W.L., J.Y., X.H., W.R., J.Z., M.G., W.W., Y.T.), Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, China; National Clinical Research Center for Ocular Diseases (L.C., Y.S., W.L., J.Y., X.H., W.R., J.Z., M.G., W.W., Y.T.), Eye Hospital, Wenzhou Medical University, Wenzhou, China. Electronic address:
Purpose: To gauge the efficacy and safety of performing a one-stage endoscopic orbital decompression procedure combined with the intraoperative relaxed medial rectus muscle (MR) positioning technique as a means of treating esotropia associated with thyroid-associated ophthalmopathy (TAO).
Design: Prospective, single-blind, randomized controlled trial.
Setting: Eye Hospital of Wenzhou Medical University.
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