An ulcerated and pedunculated intraluminal yellowish solitary mass was observed protruding into the ruminal lumen of an adult cow during an abattoir survey. Histologically, the neoplasm invaded the lamina propria-submucosa, eroded the ruminal epithelium and segmentally effaced the inner tunica muscularis. It was composed of pleomorphic spindle cells arranged in fascicles. Areas of hemorrhage, necrosis, microcystic changes as well as marked anisokaryosis, the presence of giant cells and scattered mitosis with atypical figures, were also observed. Immunohistochemically this tumor labeled positive for alpha smooth muscle actin, desmin and vimentin. With all the above findings, a diagnosis of ruminal leiomyosarcoma was confirmed. To the authors' knowledge, this is the first report of ruminal leiomyosarcoma in cattle.
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J Vet Diagn Invest
November 2024
California Animal Health and Food Safety Laboratory, School of Veterinary Medicine, University of California-Davis, San Bernardino Branch, San Bernardino, CA, USA.
A mass was removed surgically from the right orbit of a 1-d-old Holstein calf. Grossly, the mass filled the rostral part of an enlarged orbit and compressed the globe toward the caudal pole of the orbit. The brown, 6-cm tumor had central yellow and brown areas, and a smooth, glistening cut surface.
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May 2023
Department of Veterinary Clinic and Pathology, Faculty of Veterinary Medicine, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.
A 12-year-old Saanen goat presented with a history of hyporexia and sudden recumbency. Euthanasia was indicated due to suspicion of hepatic neoplasia associated with senility. Necropsy revealed generalized oedema and increased liver size and weight (33 × 38 × 17 cm and 10.
View Article and Find Full Text PDFVet Radiol Ultrasound
March 2023
Department of Clinical Sciences, Oregon Veterinary Diagnostic Laboratory, Corvallis, Oregon, USA.
Neoplasia of the tubular genital tract in goats, while rarely described, is most commonly reported as uterine adenocarcinoma, leiomyoma, or leiomyosarcoma. In this retrospective, single-center, case series, medical records were searched for goats with a computed tomography (CT) diagnosis of tubular genital mass and a definitive histologic (surgical biopsy or necropsy) diagnosis of malignant neoplasia. Data recorded from CT images were presence of peritoneal/retroperitoneal fluid, urinary tract obstruction, abdominal lymphadenomegaly, additional abdominal nodules/masses, and pulmonary nodules.
View Article and Find Full Text PDFCan Vet J
August 2022
Department of Large Animal Clinical Sciences (Guardado, Gabadage) and Department of Veterinary Pathology (Allen), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan.
A 14-month-old feedlot steer was depressed and died while being examined. The gross post-mortem examination of the steer conducted at the feedlot identified numerous masses within the abdomen and thorax, including a large mass in the liver that eroded into the vena cava. Many masses in the lungs appeared to be the result of hematogenous distribution.
View Article and Find Full Text PDFJ Vasc Surg Venous Lymphat Disord
May 2022
Division of Vascular Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Ill. Electronic address:
Objective: Primary leiomyosarcoma of the inferior vena cava (IVC) is best managed with surgical resection when technically feasible. However, consensus is lacking regarding the best choice of conduit and reconstruction technique. The aim of the present multicenter study was to perform a comprehensive assessment through the VLFDC (Vascular Low Frequency Disease Consortium) to determine the most effective method for caval reconstruction after resection of primary leiomyosarcoma of the IVC.
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