AI Article Synopsis
- A study analyzed data from 401 overweight and obese adults in a weight loss program to investigate the cardiovascular effects of modest weight loss (5-10%).
- Participants who lost 5-10% of their body weight showed significant reductions in triglycerides, total cholesterol, and LDL cholesterol compared to those who lost more than 10%, who experienced even greater improvements.
- For higher-risk individuals, losing 5-10% led to significant reductions in fasting glucose and other risk factors, while losses over 10% resulted in even better outcomes across multiple cardiovascular indicators (except HDL cholesterol).
Article Abstract
Little is known about the cardiovascular effects of modest weight loss. To determine whether weight losses limited to 5-10 % are sufficient to produce cardiovascular health benefits, data from 401 overweight and obese adults who enrolled in a behavioral weight loss program from 2003 to 2011 were analyzed. Primary outcomes were changes in fasting glucose, triglycerides, and cholesterol. Patients who lost 5-10 % showed significant reductions in triglycerides, total cholesterol, and low-density lipoprotein (LDL) cholesterol. Patients who lost >10 % experienced significantly greater improvements in triglycerides, total cholesterol, and LDL cholesterol than patients losing less. For higher-risk patients, those who lost 5-10 % significantly reduced fasting glucose, triglycerides, and total cholesterol; those who lost >10 % improved on all risk factors (except HDL cholesterol) and to a significantly greater degree than those losing less. Five to 10 % weight losses produced improvements in cardiovascular risk factors, but greater weight losses were associated with even greater improvement.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987606 | PMC |
| http://dx.doi.org/10.1007/s13142-015-0353-9 | DOI Listing |
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