AI Article Synopsis
- The study examines the impact of laparoscopic cystectomy (LC) on pregnancy outcomes and ovarian reserve in women with ovarian endometrioma (OE) by measuring anti-Müllerian hormone (AMH) levels.
- Among 40 women with OE, cumulative pregnancy rates were 50%, but AMH levels were notably lower pre- and post-surgery compared to a non-endometrioma group, especially in women over 35.
- While LC is considered a favorable surgical option, there is a need for strategies to preserve ovarian reserve, particularly for older patients.
Article Abstract
Aim: Excision of ovarian endometrioma (OE) may induce the reduction of ovarian reserve. We evaluated pregnancy outcomes after laparoscopic cystectomy (LC), and the pre- and postoperative levels of anti-Müllerian hormone (AMH) to consider the ovarian reserve.
Methods: We enrolled 40 women with OE and 16 women with benign ovarian tumors who hoped to have a child and who underwent LC. To evaluate the ovarian reserve of 40 patients (OE group, n = 24; non-OE group, n = 16), we measured serum AMH levels before and after the surgery.
Results: In the 40 women who underwent LC for OE, the cumulative pregnancy rate was 50%. Prior to the cystectomy, serum AMH levels in the OE group, especially in patients over the age of 35, were significantly lower than those in the non-OE group. Rate of decline in serum AMH in the OE group was significant compared with that in the non-OE group 6 months after surgery. In patients over the age of 35 in the OE group, AMH levels 1 year after surgery decreased noticeably.
Conclusion: LC for OE could be a preferred surgical approach, but effective therapeutic strategies will have to be developed to prevent damage to the ovarian reserve, especially for older patients.
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| http://dx.doi.org/10.1111/jog.13081 | DOI Listing |
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