AI Article Synopsis
- This study compared muscle oxygen dynamics during exercise between elderly patients with angina pectoris (AP) and matched controls.
- AP patients showed higher muscle oxygen saturation (SmO2) and lower deoxygenated hemoglobin concentrations (∆deoxy-Hb) during exercise compared to the control group.
- There was a negative correlation between changes in SmO2 and peak oxygen uptake (VO2), indicating that AP patients have a blunted muscle deoxygenation response which may be linked to their reduced aerobic capacity.
Article Abstract
Muscle O2 dynamics during ramp cycling exercise were compared between angina pectoris patients (AP; n = 7, age: 73 ± 6 years) after coronary artery bypass grafting and age-, height-, and body weight-matched elderly control subjects (CON; n = 7, age: 74 ± 8 years). Muscle O2 saturation (SmO2) and relative change in deoxygenated (∆deoxy-Hb) and total hemoglobin concentration (∆total-Hb) were measured continuously during exercise in the vastus lateralis (VL) by near infrared spatial resolved spectroscopy. Pulmonary O2 uptake (VO2) was also monitored throughout exercise to determine peak VO2. In AP, SmO2 was significantly higher, and ∆deoxy-Hb was significantly lower during exercise, compared to CON. In all subjects, ∆SmO2 (values at peak exercise minus values at resting) was negatively correlated to peak VO2 (r = -0.52, p < 0.05), and ∆deoxy-Hb at peak exercise tended to be negatively associated with peak VO2 (r = 0.48, p = 0.07). Blunted skeletal muscle deoxygenation response was observed in AP patients, which may be related to lower aerobic capacity in AP patients.
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| http://dx.doi.org/10.1007/978-3-319-38810-6_39 | DOI Listing |
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