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Maintenance eculizumab dose adjustment in the treatment of atypical hemolytic uremic syndrome: a case report and review of the literature. | LitMetric
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Maintenance eculizumab dose adjustment in the treatment of atypical hemolytic uremic syndrome: a case report and review of the literature.

Nick Thomson Matthew Ulrickson

Clin Case Rep

Department of Hematology/Oncology Banner MD Anderson Cancer Center Gilbert Arizona USA.

Published: August 2016

Atypical hemolytic uremic syndrome (aHUS) patients treated with eculizumab may require higher doses to achieve and maintain optimal clinical response. Further studies are warranted to elucidate optimal dosing regimens of eculizumab in aHUS patients, and whether dosing regimens can be predicted based on mutational status, eculizumab levels, or other testing.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974426PMC
http://dx.doi.org/10.1002/ccr3.628DOI Listing

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